000			03046nam a22003257a 4500
999			_c112518 _d112518
003			IE-CoIT
005			20181023101941.0
008			181018s2018 ie ||||| |||| 00| 0|eng||
040			_aIE-CoIT
082			_aTHESES PRESS
100	1		_9125510 _aTuck, Sarah _eauthor
245	1	0	_aDevelopment of multi-class analytical methods for agrochemical contaminants / _cSarah Tuck.
264		1	_aCork : _bCork Institute of Technology, _c2018.
300			_axxiii, 345 pages : _billustrations ; _c30 cm
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
490	0		_aPh.D - Chemistry
502			_aThesis _b(Ph.D.) - _cCork Institute of Technology, _d2018.
504			_aBibliography: (pages 250-279)
520	3		_a'In this project, cost-effective multi-class analytical methods were developed to detect a range of antiparasitic, feed additives and pesticide substances in foodstuffs of animal origin. These substances have the potential to enter the food chain through their occurrence as residues either through the animal themselves or other routes e.g. contamination. To ensure the continued safety of food destined for human consumption regulatory control limit have been established for permitted levels of these residues in foods of animal origin. Despite these controls the continued monitoring of foodstuffs is necessary to ensure these limits are not breached and that substances are not administered except as approved to food producing animals. In this work an analytical method for the detection of pyrethrin and pyrethroid residues in the fat of different animal species was developed. This was advantageous in that, residues such as tralomethrin and flumethrin not easily assessed by GC could be directly analysed by LC. In addition this method employed green chemistry which allowed for minimal solvent usage, reduced waste outputs, improved sample throughput and improved laboratory turnaround times. To take advantage of this economic and sensitive method it was extended to the analysis of pesticide residues in honey matrices. A new automated high-throughput sample preparation protocol for the detection and quantification of anthelmintic residues in animal tissue was also developed. This was a significant contribution to the area of residue control as the use of automated steps allowed for a reduction in method variability and improved sample throughput for laboratories. Finally a new HILIC approach for the analysis of polar anticoccidial residues in animal muscle was developed and an older C8 approach updated to include a larger number of analytes'. Abstract
650		0	_933767 _aAgricultural chemicals _xAnalysis
650		0	_993634 _aFood of animal origin _xContamination
650		0	_993635 _aVeterinary drug residues
650		0	_976790 _aPesticide residues in food
650		0	_937689 _aGas chromatography
650		0	_939280 _aLiquid chromatography
650		0	_9125514 _aHydrophilic interaction liquid chromatography
942			_2ddc