Molecular genetics mycobacteria / edited by Graham F. Hatfull and William R. Jacobs.
Contributor(s): Hatfull, Graham F [editor] | Jacobs, William R., Jr [editor].
Material type: BookPublisher: Washington, DC : ASM Press, [2000]Copyright date: ©2000Description: xii, 363 pages : illustrations (some color) 29 cm.Content type: text Media type: unmediated Carrier type: volumeISBN: 9781555811914 (hardback); 1555811914 (hardback).Subject(s): Mycobacteria | Bacterial genetics | Tuberculosis -- Genetic aspectsDDC classification: 579.374Item type | Current library | Call number | Copy number | Status | Date due | Barcode | Item holds |
---|---|---|---|---|---|---|---|
General Lending | MTU Bishopstown Library Lending | 579.374 (Browse shelf(Opens below)) | 1 | Available | 00086358 |
Enhanced descriptions from Syndetics:
A new specialist research-level monograph, discussing mycobacterial genetics in
Includes bibliographical references and index.
Introduction: Mycobacterium tuberculosis: a Once Genetically Intractable Organism -- Genomes and genetic exchange -- Genomics, biology, and evolution of the Mycobacterium tuberculosis complex -- Molecular genetics of Mycobacteriophages -- Plasmids in Mycobacteria -- Mycobacterial transposons and their applications -- General recombination -- DNA transfer in mycobacteria: conjugation and transduction -- Gene expression -- Determinants of Mycobacterial gene expression -- Gene expression: reporter technologies -- Mycobacterial transcription regulation in stationary phase -- Metabolism -- DNA replication -- Genetics of mycolic acid biosynthesis -- Genetics of cell wall biosynthesis -- Genetics of protein secretion -- Genetics of mycobacterial metabolism -- Genetics of drug resistance in mycobacterium tuberculosis -- Genetic Strategies -- Mutants and mutagenesis -- Genetics of mycobacterial virulence -- Genetic strategies for vaccine development -- Approaches to tuberculosis drug development
Table of contents provided by Syndetics
- Contributors (p. vii)
- Preface (p. x)
- Introduction: Mycobacterium tuberculosis: a Once Genetically Intractable Organism (p. 1)
- Genomes and Genetic Exchange
- 1 Genomics, Biology, and Evolution of the Mycobacterium tuberculosis Complex (p. 19)
- 2 Molecular Genetics of Mycobacteriophages (p. 37)
- 3 Plasmids in Mycobacteria (p. 55)
- 4 Mycobacterial Transposons and Their Applications (p. 69)
- 5 General Recombination (p. 85)
- 6 DNA Transfer in Mycobacteria: Conjugation and Transduction (p. 93)
- Gene Expression
- 7 Determinants of Mycobacterial Gene Expression (p. 111)
- 8 Gene Expression: Reporter Technologies (p. 131)
- 9 Mycobacterial Transcription Regulation in Stationary Phase (p. 149)
- Metabolism
- 10 DNA Replication (p. 159)
- 11 Genetics of Mycolic Acid Biosynthesis (p. 173)
- 12 Genetics of Cell Wall Biosynthesis (p. 191)
- 13 Genetics of Protein Secretion (p. 203)
- 14 Genetics of Mycobacterial Metabolism (p. 221)
- 15 Genetics of Drug Resistance in Mycobacterium tuberculosis (p. 235)
- Genetic Strategies
- 16 Mutants and Mutagenesis (p. 257)
- 17 Genetics of Mycobacterial Virulence (p. 265)
- 18 Genetic Strategies for Vaccine Development (p. 279)
- 19 Approaches to Tuberculosis Drug Development (p. 297)
- Appendixes
- 1 Some Common Methods in Mycobacterial Genetics (p. 313)
- 2 Internet Sites with Further Information on Mycobacterial Genetics (p. 321)
- 3 Genome Organization of Mycobacterium tuberculosis H37Rv (p. 323)
- Index (p. 355)