MTU Cork Library Catalogue

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Development of novel antimicrobial agents : emerging strategies / edited by Karl Lohner.

Contributor(s): Lohner, Karl.
Material type: materialTypeLabelBookPublisher: Norfolk, England : Horizon Scientific Press, 2001Description: xi, 284 p. : ill. ; 25 cm. + hbk.ISBN: 1898486239 .Subject(s): Anti-infective agents | Antibiotics | Drug resistance in microorganismsDDC classification: 615.329
Contents:
Section 1 The problem of antimicrobial resistance: Are we on the threshold of the post-antibiotic era? / Karl Lohner and Erich Staudegger -- Origins and evolution of antibiotic and multiple antibiotic resistance in bacteria / Ruth M. Hall and Christina M. Collis -- Antimicrobial peptide resistance mechanisms in bacteria / Arden Aspedon and Eduardo A. Groisman -- Section 2 Microbial genomics: novel targets and vaccines: Genetic engineering of novel macrolide antibiotics / Robert McDaniel and Leonard Katz -- Granulysin, a novel mediator of antimicrobial activity of cytolytic t-cells / Steffen Stenger, Alan M. Krensky and Robert L. Modlin -- The immunostimulatory properties of bacterial DNA / David S. Pisetsky -- Bacteria-mediated DNA transfer for gene therapy and genetic vaccination / Siegfried Weiss and Trinad Chakraborty -- Potential mucosal adjuvants for human use / Mari Ohmura, Raymond J. Jackson, Yoshifumi Takeda and Jerry R. McGhee -- Attenuated bacteria as delivery vehicles for Helicobacter pylori vaccines / Thomas G. Blanchard and Steven J. Czinn -- Development of an adhesin vaccine to prevent urinary tract infection / Matthew A. Mulvey, Scott J. Hultgren and Solomon Langermann -- Section 3 Innate immunity: antimicrobial peptides: Antimicrobial peptides in innate immunity / Tomas Ganz and Robert I. Lehrer -- The role of membrane lipid composition in cell targeting of antimicrobial peptides / Karl Lohner -- Molecular mechanisms of membrane perturbation by antimicrobial peptides / Katsumi Matsuzaki -- Molecular mechanism of cell selectively by linear amphipatic x-helical and diasteriomeric antimicrobial peptides / Ziv Oren and Yechiel Shai -- Molecular interactions involved in bactericidal activities of lantibiotics / Ulrike Pag and Hans-Georg Sahl -- Cyclic cystine-knot -stranded antimicrobial peptides: occurence, design and synthesis / James P. Tam, Yi-An Lu, Jin-Long Yang and Qitao Yu -- Synthetic combinatorial libraries: an emerging approach toward the identification of novel antibiotics / Sylvie E. Blondelle -- The commercial development of the antimicrobial peptide pexiganan / Michael Zasloff.
Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
General Lending MTU Bishopstown Library Lending 615.329 (Browse shelf(Opens below)) 1 Available 00086423
General Lending MTU Bishopstown Library Lending 615.329 (Browse shelf(Opens below)) 1 Available 00086422
Total holds: 0

Enhanced descriptions from Syndetics:

This book presents current research on the development of new classes of antibiotics with novel mechanisms of action. Leading international researchers from academia and industry present this unique collection of highly acclaimed reviews covering every aspect of this important topic. The authors also discuss strategies for the containment of antimicrobial resistance, and advocate a more sophisticated and prudent use of antibiotics.

Includes bibliographical references and index.

Section 1 The problem of antimicrobial resistance: Are we on the threshold of the post-antibiotic era? / Karl Lohner and Erich Staudegger -- Origins and evolution of antibiotic and multiple antibiotic resistance in bacteria / Ruth M. Hall and Christina M. Collis -- Antimicrobial peptide resistance mechanisms in bacteria / Arden Aspedon and Eduardo A. Groisman -- Section 2 Microbial genomics: novel targets and vaccines: Genetic engineering of novel macrolide antibiotics / Robert McDaniel and Leonard Katz -- Granulysin, a novel mediator of antimicrobial activity of cytolytic t-cells / Steffen Stenger, Alan M. Krensky and Robert L. Modlin -- The immunostimulatory properties of bacterial DNA / David S. Pisetsky -- Bacteria-mediated DNA transfer for gene therapy and genetic vaccination / Siegfried Weiss and Trinad Chakraborty -- Potential mucosal adjuvants for human use / Mari Ohmura, Raymond J. Jackson, Yoshifumi Takeda and Jerry R. McGhee -- Attenuated bacteria as delivery vehicles for Helicobacter pylori vaccines / Thomas G. Blanchard and Steven J. Czinn -- Development of an adhesin vaccine to prevent urinary tract infection / Matthew A. Mulvey, Scott J. Hultgren and Solomon Langermann -- Section 3 Innate immunity: antimicrobial peptides: Antimicrobial peptides in innate immunity / Tomas Ganz and Robert I. Lehrer -- The role of membrane lipid composition in cell targeting of antimicrobial peptides / Karl Lohner -- Molecular mechanisms of membrane perturbation by antimicrobial peptides / Katsumi Matsuzaki -- Molecular mechanism of cell selectively by linear amphipatic x-helical and diasteriomeric antimicrobial peptides / Ziv Oren and Yechiel Shai -- Molecular interactions involved in bactericidal activities of lantibiotics / Ulrike Pag and Hans-Georg Sahl -- Cyclic cystine-knot -stranded antimicrobial peptides: occurence, design and synthesis / James P. Tam, Yi-An Lu, Jin-Long Yang and Qitao Yu -- Synthetic combinatorial libraries: an emerging approach toward the identification of novel antibiotics / Sylvie E. Blondelle -- The commercial development of the antimicrobial peptide pexiganan / Michael Zasloff.

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