Principles of medicinal chemistry / [edited by] William O. Foye, Thomas L. Lemke and David A. Williams.
Contributor(s): Foye, William O
| Lemke, Thomas L | Williams, David A.
Material type: 
BookPublisher: Philadelphia ; London : Lippincott Williams & Wilkins, c1995Edition: 4th ed.Description: xii, 995 p. : ill ; 29 cm. + hbk.ISBN: 0683033239.Subject(s): Pharmaceutical chemistryDDC classification: 615.7 | Item type | Current library | Call number | Copy number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|---|
| General Lending | MTU Bishopstown Library Lending | 615.7 (Browse shelf(Opens below)) | 1 | Available | 00075043 |
Enhanced descriptions from Syndetics:
This new edition features two new co-authors, extensive revision of the text and current information from the field of medicinal chemistry. It is intended for students of pharmacy.
Includes bibliographical references and index.
Introduction and history / William O. Foye -- Medicinals of plant origin: historical aspects / William O. Foye -- Biopharmaceutical properties of drug substances / Sunil S. Jambhekar -- Structural features and pharmacologic activity / Ian W. Mathison, William E. Solomons and Richard R. Tidwell -- Theoretic aspects of drug design / Michael S. Tute and Lemont B. Kier -- Molecular modeling / James G. Henkel and Eric M. Billings -- Receptors and drug action / Timothy J. Maher -- Drug metabolism / David A. Williams -- Volatile anesthetics / Ronald L. Jacoby and Karl A. Nieforth -- Central nervous system depressants: sedative-hypnotics / Julius A. Vida -- Anticonvulsants / Julius A. Vida -- Neuroleptics and anxiolytic agents / John L. Neumeyer and Raymond G. Booth -- Drugs used to treat neuromuscular disorders: antiparkinsonism agents and skeletal muscle relaxants / John L. Neumeyer and Raymond G. Booth -- Analgesics / David S. Fries -- Central nervous system stimulants / Karl A. Nieforth and Gerald Gianutsos -- Local anesthetics / Matthias C. Lu -- Cholinergic agonists, acetylcholinesterase inhibitors and cholinergic antagonists / Danny L. Lattin -- Adrenergic drugs / Robert K. Griffith and Elizabeth A. Johnson -- Cardiac agents: cardiac glycosides, antianginals and antiarrhythmic drugs / Ahmed S. Mehanna -- Anticoagulants, coagulants and plasma extenders / Richard H. Hammer -- Diuretics / Gary O. Rankin -- Antiallergic and antiulcer drugs / Maria Di Bella, Daniela Braghiroli and Donald T. Witiak -- Cholesterol, adrenocorticoids and sex hormones / Robert W. Brueggemeier, Duane D. Miller and Donald T. Witiak -- Antilipidemic drugs / Dennis R. Feller, Larry M. Hagerman, Howard A. I. Newman and Donald T. Witiak -- Nonsteroidal anti-inflammatory drugs / Ronald F. Borne -- Drugs affecting sugar metabolism / Edmund J. Hengesh -- Amino acids, peptides and proteins / Roy L. Kisliuk -- Pharmaceutical biotechnology / Robert D. Sindelar -- Vitamins and coenzymes / Raymond W. Doskotch and Robert W. Curley, Jr. -- Thyroid function and thryoid drugs / Alireza Banijamali -- Metabolite antagonism / Nitya Anand -- Parasite chemotherapy / William O. Foye -- Antimycobacterial agents / Thomas L. Lemke -- Antibiotics and antimicrobial agents / Lester A. Mitscher -- Antifungal agents / Eugene D. Weinberg -- Antiseptics and disinfectants / Thomas L. Lemke -- Cancer chemotherapy / William O. Foye and Sisir K. Sengupta -- Antiviral agents / Manohar L. Sethi -- Approaches to anti-AIDS agents / Prem Mohan -- Hormone antagonists / V. Craig Jordan -- Photochemotherapy / Francesco Dall'Acqua and Giulio Jori -- Pesticides / John L. Neumeyer and Raymond G. Booth -- Agents for organ imaging / Raymond E. Counsell and Jamey P. Weichert.
Table of contents provided by Syndetics
- 1. Introduction and History (p. 1)
- 2. Medicinals of Plant Origin: Historical Aspects (p. 7)
- 3. Biopharmaceutical Properties of Drug Substances (p. 12)
- 4. Structural Features and Pharmacologic Activity (p. 25)
- 5. Theoretic Aspects of Drug Design (p. 50)
- 6. Molecular Modeling (p. 58)
- 7. Receptors and Drug Action (p. 75)
- 8. Drug Metabolism (p. 83)
- 9. Volatile Anesthetics (p. 141)
- 10. Central Nervous System Depressants: Sedative-Hypnotics (p. 154)
- 11. Anticonvulsants (p. 182)
- 12. Neuroleptics and Anxiolytic Agents (p. 199)
- 13. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonism Agents and Skeletal Muscle Relaxants (p. 232)
- 14. Analgesics (p. 247)
- 15. Central Nervous System Stimulants (p. 270)
- 16. Local Anesthetics (p. 305)
- 17. Cholinergic Agonists, Acetylcholinesterase Inhibitors, and Cholinergic Antagonists (p. 321)
- 18. Adrenergic Drugs (p. 345)
- 19. Cardic Agents: Cardiac Glycosides, Antianginals, and Antiarrhythmic Drugs (p. 366)
- 20. Anticoagulants, Coagulants, and Plasma Extenders (p. 388)
- 21. Diuretics (p. 405)
- 22. Antiallergic and Antiulcer Drugs (p. 416)
- 23. Cholesterol, Adrenocorticoids, and Sex Hormones (p. 444)
- 24. Antilipidemic Drugs (p. 499)
- 25. Nonsteroidal Anti-inflammatory Drugs (p. 535)
- 26. Drugs Affecting Sugar Metabolism (p. 581)
- 27. Amino Acids, Peptides, and Proteins (p. 601)
- 28. Pharmaceutical Biotechnology (p. 622)
- 29. Vitamins and Coenzymes (p. 652)
- 30. Thyroid Function and Thyroid Drugs (p. 688)
- 31. Metabolite Antagonism (p. 705)
- 32. Parasite Chemotherapy (p. 730)
- 33. Antimycobacterial Agents (p. 747)
- 34. Antibiotics and Antimicrobial Agents (p. 759)
- 35. Antifungal Agents (p. 803)
- 36. Antiseptics and Disinfectants (p. 812)
- 37. Cancer Chemotherapy (p. 822)
- 38. Antiviral Agents (p. 846)
- 39. Approaches to Anti-AIDS Agents (p. 862)
- 40. Hormone Antagonists (p. 877)
- 41. Photochemotherapy (p. 893)
- 42. Pesticides (p. 908)
- 43. Agents for Organ Imaging (p. 927)
- Appendix (p. 948)
- pK[subscript a] Values for Some Drugs and Miscellaneous Organic Acids and Bases
- pH Values for Tissue Fluids
- Index (p. 963)