Part I Molecular design of life: Prelude -- Protein structure and function -- Exploring proteins -- DNA and RNA: molecules of heredity -- Flow of genetic information -- Exploring genes -- Part II Proteins: conformation, dynamics and function: Portrait of an allosteric protein -- Enzymes: basic concepts and kinetics -- Catalytic strategies -- Regulatory strategies -- Membrane structure and dynamics -- Membrane channels and pumps -- Signal transduction cascades -- Antibodies and t-cell receptors -- Molecular motors -- Protein folding and design -- Part III Metabolic energy: generation and storage: Metabolism: basic concepts and design -- Carbohydrates -- Glycolysis -- Citric acid cycle -- Oxidative phosphorylation -- Pentose phosphate pathway and gluconeogenesis -- Glycogen metabolism -- Fatty acid metabolism -- Amino acid degradation and the urea cycle -- Photosynthesis -- Part IV Biosynthesis of building blocks: Biosynthesis of membrane lipids and steroids -- Biosynthesis of amino acids and heme -- Biosynthesis of nucleotides -- Integration of metabolism -- Part V Genes: Replication and expression: DNA structure, replication and repair -- Gene rearrangements -- RNA synthesis and splicing -- Protein synthesis -- Protein targeting -- Control of gene expression in prokaryotes -- Eukaryotic chromosomes and gene expression.