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Biochemical targets of plant bioactive compounds [electronic book] : a pharmacological reference guide to sites of action and biological effects / Gideon Polya.

By: Polya, Gideon Maxwell.
Material type: materialTypeLabelBookPublisher: London ; New York : Taylor & Francis, 2003Description: online resource (xii, 847 pages) : illustrations.Content type: text Media type: computer Carrier type: online resourceISBN: 0415308291 (hardback); 9780203013717 (e-book).Subject(s): Materia medica, Vegetable -- Handbooks, manuals, etc | Botanical chemistry -- Handbooks, manuals, etc | Plant products -- Handbooks, manuals, etc | Pharmacognosy -- Handbooks, manuals, etc | Plants -- Metabolism -- Handbooks, manuals, etcGenre/Form: Electronic booksAdditional physical formats: Print version:.: Biochemical targets of plant bioactive compoundsDDC classification: 615.32 Online resources: E-book Also available in print form.
Contents:
Plant defensive compounds and their biochemical targets -- Introduction -- Organization and scope of the book -- Description of the tables -- Using the tables -- The structural diversity of plant defensive compounds -- Plant alkaloids -- Plant phenolics -- Plant terpenes -- Other plant compounds -- Biochemistry: the chemistry of life -- Introduction: water-based life -- Protein structure -- Enzymes and ligand-binding proteins -- Metabolic strategies -- Inhibition of biochemical processes by plant defensive compounds -- Neurotransmitter- and hormone-gated ion channels -- Introduction: electrical signalling in excitable cells -- Ionotropic neurotransmitter receptors: neurotransmitter-gated ion channels -- Structure and function of ionotropic receptors -- Ion pumps, ligand- and voltage-gated ion channels -- Introduction -- Ion pumps -- Voltage-gated Na+ channels -- Ligand-regulated and voltage --gated K+ channels -- Voltage-gated Ca²+ channels -- Ligand-gated Ca²+ channels -- Chloride transport and voltage-regulated chloride channels.
Summary: When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents.
List(s) this item appears in: E-BOOK LIST
Holdings
Item type Current library Call number Status Date due Barcode Item holds
e-BOOK MTU Bishopstown Library eBook 615.32 (Browse shelf(Opens below)) Not for loan
Total holds: 0

Enhanced descriptions from Syndetics:

When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents.

Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.

Includes bibliographical references and indexes.

Plant defensive compounds and their biochemical targets -- Introduction -- Organization and scope of the book -- Description of the tables -- Using the tables -- The structural diversity of plant defensive compounds -- Plant alkaloids -- Plant phenolics -- Plant terpenes -- Other plant compounds -- Biochemistry: the chemistry of life -- Introduction: water-based life -- Protein structure -- Enzymes and ligand-binding proteins -- Metabolic strategies -- Inhibition of biochemical processes by plant defensive compounds -- Neurotransmitter- and hormone-gated ion channels -- Introduction: electrical signalling in excitable cells -- Ionotropic neurotransmitter receptors: neurotransmitter-gated ion channels -- Structure and function of ionotropic receptors -- Ion pumps, ligand- and voltage-gated ion channels -- Introduction -- Ion pumps -- Voltage-gated Na+ channels -- Ligand-regulated and voltage --gated K+ channels -- Voltage-gated Ca²+ channels -- Ligand-gated Ca²+ channels -- Chloride transport and voltage-regulated chloride channels.

When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents.

CIT Module BIOL 8009 - Supplementary reading.

Also available in print form.

Electronic reproduction.: ProQuest LibCentral. Mode of access: World Wide Web.

Table of contents provided by Syndetics

  • Plant Defensive Compounds and their Molecular Targets
  • Introduction
  • Organization and Scope of the Book
  • Description of the Tables
  • Using the Tables
  • The Structural Diversity of Plant Defensive Compounds
  • Plant Alkaloids
  • Plant Phenolics
  • Plant Terpenes
  • Other Plant Compounds
  • Biochemistry - The Chemistry of Life
  • Introduction - Water-based Life
  • Protein Structure
  • Enzymes and Ligand-binding Proteins
  • Metabolic Strategies
  • Inhibition of Biochemical Processes by Plant Defensive Compounds
  • Neurotransmitter- and Hormone-Gated Ion Channels
  • Introduction - Electrical Signaling in Excitable Cells
  • Ionotropic Neurotransmitter Receptors - Neurotransmitter-gated Ion Channels
  • Structure and Function of Ionotropic Receptors
  • Ion Pumps, Ligand- and Voltage-Gated Ion Channels
  • Introduction
  • Ion Pumps
  • Voltage-gated Na+ Channels
  • Ligand-Regulated and Voltage-gated K+ Channels
  • Voltage-gated Ca2+ Channels
  • Ligand-gated Ca2+ Channels
  • Chloride Transport and Voltage-regulated Chloride Channels
  • Plasma Membrane G Protein-Coupled Receptors
  • Introduction - Signaling Via Heterotrimeric G Proteins
  • G Protein-coupled Hormone and Neurotransmitter Receptors
  • Hormones and Neurotransmitters Acting Via G Protein-coupled Receptors
  • Activation of Specific G Protein-coupled Receptors
  • Leucocyte- and Inflammation-related G Protein-linked Receptors
  • Other G Protein-coupled Receptors
  • Neurotransmitter Transporters and Converters
  • Introduction
  • Synthesis of Neurotransmitters
  • Release of Neurotransmitters from Synaptic Vesicles
  • Re-uptake of Neurotransmitters into Neurons and Synaptic Vesicles
  • Neurotransmitter Degradation
  • Cyclic Nucleotide-, Ca2+- and Nitric Oxide-Based Signaling
  • Introduction
  • Ca2+- and Calmodulin-dependent Enzymes
  • Adenylyl Cyclase
  • Membrane-bound and Soluble Guanylyl Cyclases
  • Nitric Oxide Synthesis
  • Cyclic AMP- and Cyclic GMP-dependent Protein Kinases
  • Protein Kinase Homologies and Phosphoprotein Phosphatases
  • Cyclic Nucleotide Phosphodiesterases
  • Signal-Regulated Protein Kinases
  • Introduction
  • Cyclic AMP-dependent Protein Kinase
  • Cyclic GMP-dependent Protein Kinase
  • Protein Kinase C
  • Ca2+ -calmodulin-dependent Protein Kinases
  • AMP-dependent Protein Kinase
  • Receptor Tyrosine Kinases
  • Protein Kinase B
  • Cytokine Activation of the JAK/STAT Pathway
  • Cell Cycle Control
  • Receptor Serine/Threonine Kinases
  • Other Protein Kinases
  • Phosphoprotein Phosphatases
  • Gene Expression, Cell Division and Apoptosis
  • Introduction
  • Regulation of Gene Expression in Prokaryotes
  • Regulation of Transcription in Eukaryotes
  • RNA Processing and Translation
  • Control of Translation
  • Protein Processing and Post-translational Modification
  • Protein Targeting
  • Cell Division and Apoptosis
  • HIV-1 Infection and HIV-1 Replication
  • Plant Compounds Interfering with Gene Expression
  • Taste and Smell Perception, Pheromones and Semiochemicals
  • Introduction
  • Sweet Taste Receptors
  • Bitter Taste Receptors
  • Salty Taste Perception
  • Sour Taste Perception
  • Umami (Glutamate Taste Perception)
  • Odorant Perception
  • Animal Pheromones and Other Animal Bioactivities Produced by Plants
  • Other Plant Semiochemicals Affecting Animal Behavior
  • Odoriferous Animal Metabolites of Ingested Plant Compounds
  • Agonists and Antagonists of Cytosolic Hormone Receptors
  • Introduction
  • Steroid Hormones
  • Non-steroid Cytosolic Hormone Receptor Ligands
  • Plant Bioactives Affecting Cyctosolic Receptor-mediated Signaling
  • Polynucleotides, Polysaccharides, Phospholipids and Membranes
  • Introduction
  • Polynucleotides
  • Polysaccharides and Oligosaccharides
  • Phospholipids and Membranes
  • Inhibitors of Digestion and Metabolism
  • Introduction
  • Glycohydrolases
  • Proteases
  • Glycolysis and Tricarboxylic Acid Cycle
  • Mitochondrial Electron Transport and Oxidative Phosphorylation
  • Gluconeogenesis
  • Solute Translocation
  • Anti-Inflammatory, Antioxidant and Antidiabetic Plant Compounds
  • Introduction
  • Adhesion and Movement of Inflammatory Leucocytes
  • Chemokines
  • Phagocytosis
  • Kinins, Cytokines, Platelet Activating Factor and Eicosanoids
  • Plant-derived Anti-inflammatory Compounds
  • Diabetes Mellitus and Plant Antidiabetic Compounds
  • Summary
  • Appendix
  • Bibliography
  • Compound Index
  • Plant Genus Index
  • Plant Common Names Index
  • Subject Index
  • Abbreviations

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