MTU Cork Library Catalogue

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Mutation detection : a practical approach detection / edited by R.G.H. Cotton, E. Edkins and S. Forrest.

Contributor(s): Cotton, Richard G. H | Edkins, E. (Edward) | Forrest, S. (Sue).
Material type: materialTypeLabelBookSeries: Practical approach series: 188.Publisher: Oxford ; New York : IRL Press at Oxford University Press, 1998Description: xx, 242 p. : ill. ; 24 cm.ISBN: 0199636575 ; 0199636567 .Subject(s): Mutation (Biology) -- Laboratory manuals | Molecular genetics -- Laboratory manuals | Chromosome abnormalities -- Laboratory manualsDDC classification: 576.549
Contents:
Introduction / Sue Forrest -- Single-strand conformation polymorphism analysis / Kenshi Hayashi, Youji Kukita, Masakazu Inazuka and Tomoko Tahira -- Single-stranded conformation polymorphism and heteroduplex analysis / Bernard Gerrard and Michael Dean -- Comprehensive mutation detection with denaturing gradient gel electrophoresis / L. S. Lerman and Cherif Beldjord -- Cleavage using RNase to detect mutations / H. Nagase and Y. Nakamura -- Cleavage of mismatched bases using chemical reagents / Francesco Giannelli, Peter M. Green and Susan J. Ramus -- Mutation detection using T4 endonuclease VII / Rima Youil -- Detection of mutations by hybridization with sequence-specific oligonucleotide probes / Randall K. Saiki and Henry A. Erlich -- DNA detection and sequence distinction through oligonucleotide ligation / Ulf Landegren, Martina Samiotaki, Marek Kwiatkowski, Juri Parik, Mats Nilsson, Anette Hagberg and Gisela Barbany -- Detection of sequence variation using primer extension / Ann-Christine Syvanen -- Selective amplification of specific alleles / Cynthia D. K. Bottema and Steve S. Sommer -- The protein truncation test (PTT) / Rob B. van der Luijt, Riccardo Fodde and Johan T. den Dunnen -- Functional assay of the p53 tumour suppressor gene / Thierry Frebourg, Jean-Michel Flaman, Anne Estreicher and Richard Iggo -- Advances in direct DNA sequencing for mutation scanning / Joakim Lundeberg, Cecilia Williams, Asfhin Ahmadian and Mathias Uhlen.
Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
General Lending MTU Bishopstown Library Lending 576.549 (Browse shelf(Opens below)) 1 Available 00074719
Total holds: 0

Enhanced descriptions from Syndetics:

Although important in a great many fields, mutation detection is both time-consuming and expensive. This volume offers the latest tried and tested protocols for a range of detection methods, from the labs of the leading researchers in the field.

Includes bibliographical references and index.

Introduction / Sue Forrest -- Single-strand conformation polymorphism analysis / Kenshi Hayashi, Youji Kukita, Masakazu Inazuka and Tomoko Tahira -- Single-stranded conformation polymorphism and heteroduplex analysis / Bernard Gerrard and Michael Dean -- Comprehensive mutation detection with denaturing gradient gel electrophoresis / L. S. Lerman and Cherif Beldjord -- Cleavage using RNase to detect mutations / H. Nagase and Y. Nakamura -- Cleavage of mismatched bases using chemical reagents / Francesco Giannelli, Peter M. Green and Susan J. Ramus -- Mutation detection using T4 endonuclease VII / Rima Youil -- Detection of mutations by hybridization with sequence-specific oligonucleotide probes / Randall K. Saiki and Henry A. Erlich -- DNA detection and sequence distinction through oligonucleotide ligation / Ulf Landegren, Martina Samiotaki, Marek Kwiatkowski, Juri Parik, Mats Nilsson, Anette Hagberg and Gisela Barbany -- Detection of sequence variation using primer extension / Ann-Christine Syvanen -- Selective amplification of specific alleles / Cynthia D. K. Bottema and Steve S. Sommer -- The protein truncation test (PTT) / Rob B. van der Luijt, Riccardo Fodde and Johan T. den Dunnen -- Functional assay of the p53 tumour suppressor gene / Thierry Frebourg, Jean-Michel Flaman, Anne Estreicher and Richard Iggo -- Advances in direct DNA sequencing for mutation scanning / Joakim Lundeberg, Cecilia Williams, Asfhin Ahmadian and Mathias Uhlen.

Table of contents provided by Syndetics

  • 1 Single strand conformation polymorphism analysis
  • 2 Single-stranded conformation polymorphism and heteroduplex analysis
  • 3 Comprehensive mutation detection with denaturing gradient gel electrophoresis
  • 4 Cleavage using RNase to detect mutations
  • 5 Cleavage of mismatched bases using chemical reagents
  • 6 Mutation detection using T4 endonuclease VII
  • 7 Detection of mutations by hybridization with sequence-specificoligonucleotide probes
  • 8 DNA detection and sequence distinction through oligonucleotide ligation
  • 9 Detection of sequence variation using primer extension
  • 10 Selective amplification of specific alleles
  • 11 The protein truncation text (PTT)
  • 12 Functional assay of the p53 tumour suppressor gene
  • 13 Advances in direct DNA sequencing for mutation scanning

Author notes provided by Syndetics

R. G. H.CottonMutation Research Centre, Victoria.

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