MTU Cork Library Catalogue

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Signal transduction / Bastien Gomperts, Peter Tatham and Ijsbrand Kramer.

By: Gomperts, B. D.
Contributor(s): Tatham, Peter E. R. (Life scientist) | Kramer, Ijsbrand M.
Publisher: London : Academic, 2009Edition: 2nd ed.Description: xxvii, 810 p. : col. ill. ; 26 cm. + hbk.ISBN: 9780123694416 ; 0123694418 .Subject(s): Cellular signal transductionDDC classification: 579.3
Contents:
Prologue: signal transductions, origins and ancestors -- First messengers -- Receptors -- GTP-binding proteins and signal transduction -- Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C -- The regulation of visual transduction and olfaction -- Intracellular calcium -- Calcium effectors -- Phosphorylation and dephosphorylation: protein kinases A and C -- Nuclear receptors -- Growth factors: setting the framework -- Signalling pathways operated by receptor protein tyrosine kinases -- Signal transduction to and from adhesion molecules -- Adhesion molecules in the regulation of cell differentiation: mainly about wnt -- Activation of the innate immune system: the toll-like receptor 4 and signalling through ubiquitylation -- Traffic of white blood cells -- Tyrosine protein kinases and adaptive immunity: TCR, BCR, soluble tyrosine kinases and NFAT -- Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor -- Protein kinase C revisited -- Signalling through receptor serine/threonine kinases -- Protein dephosphorylation and protein phosphorylation -- Notch -- Targeting transduction pathways for research and medical intervention -- Protein domains and signal transduction.
Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
General Lending MTU Bishopstown Library Lending 579.3 (Browse shelf(Opens below)) 1 Available 00113519
General Lending MTU Bishopstown Library Lending 579.3 (Browse shelf(Opens below)) 1 Available 00113518
General Lending MTU Bishopstown Library Lending 579.3 (Browse shelf(Opens below)) 1 Available 00105252
Total holds: 0

Enhanced descriptions from Syndetics:

Signal Transduction, 2 e, is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction, 2 e, serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.

Includes bibliographical references and index.

Prologue: signal transductions, origins and ancestors -- First messengers -- Receptors -- GTP-binding proteins and signal transduction -- Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C -- The regulation of visual transduction and olfaction -- Intracellular calcium -- Calcium effectors -- Phosphorylation and dephosphorylation: protein kinases A and C -- Nuclear receptors -- Growth factors: setting the framework -- Signalling pathways operated by receptor protein tyrosine kinases -- Signal transduction to and from adhesion molecules -- Adhesion molecules in the regulation of cell differentiation: mainly about wnt -- Activation of the innate immune system: the toll-like receptor 4 and signalling through ubiquitylation -- Traffic of white blood cells -- Tyrosine protein kinases and adaptive immunity: TCR, BCR, soluble tyrosine kinases and NFAT -- Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor -- Protein kinase C revisited -- Signalling through receptor serine/threonine kinases -- Protein dephosphorylation and protein phosphorylation -- Notch -- Targeting transduction pathways for research and medical intervention -- Protein domains and signal transduction.

CIT Module BIOL 8009 - Supplementary reading

Table of contents provided by Syndetics

  • Chapter 1 Prologue: Signal Transduction, origins and ancestors
  • Chapter 2 First messengers
  • Chapter 3 Receptors
  • Chapter 4 GTP-binding proteins and signal transduction
  • Chapter 5 Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C
  • Chapter 6 The regulation of visual transduction and olfaction
  • Chapter 7 Intracellular calcium
  • Chapter 8 Calcium effectors
  • Chapter 9 Phosphorylation and dephosphorylation: protein kinases A and C
  • Chapter 10 Nuclear receptors
  • Chapter 11 Growth Factors: setting the framework
  • Chapter 12 Signalling pathways operated by receptor protein tyrosine kinases
  • Chapter 13 Signal transduction to and from adhesion molecules
  • Chapter 14 Adhesion molecules in the regulation of cell differentiation: Mainly about Wnt
  • Chapter 15 Activation of the innate immune system: the Toll-like receptor 4 and Signalling through Ubiquitylation
  • Chapter 16 Traffic of white blood cells
  • Chapter 17 Tyrosine protein kinases and adaptive immunity : TCR, BCR, soluble tyrosine kinases and NFAT
  • Chapter 18 Phosphoinositide 3 kinases, protein kinase B and signalling through the insulin receptor
  • Chapter 19 Protein Kinase C revisited
  • Chapter 20 Signalling through receptor serine/threonine kinases
  • Chapter 21 Protein dephosphorylation and protein phosphorylation
  • Chapter 22 Notch
  • Chapter 23 Targeting transduction pathways for research and medical intervention
  • Chapter 24 Protein domains and signal transduction

Author notes provided by Syndetics

IJsbrand Kramer is a professor at the University of Bordeaux, working in the European Institute of Chemistry and Biology (IECB). He holds a Bachelors and Masters degree in BioMedicine from the University of Utrecht, The Netherlands, with a one year research-excursion in the Department of Cell Biology at the University of Liverpool, UK. He did his Ph.D. at the University of Amsterdam, in the Central Laboratory of Blood transfusion services (Stichting Sanquin) and worked as a post-doctoral fellow at the Hubrecht Laboratory in Utrecht and at the University of Washington in Seattle. He then took a lecturer position at the Department of Pharmacology at University College London, where he taught Signal Transduction (with Bastien Gomperts and Pether Tatham) and Pharmacology. Both teaching activities have been documented in textbooks: Signal Transduction (3 editions) and Receptor Pharmacology (CRC Press/Taylor Francis Group, 3 editions). Most of his research centers on the theme of inflammation, starting with neutrophils and the NADPH oxidase, synovial fibroblasts and destruction of the joint and more recently podosomes formation and extracellular matrix destruction in vascular endothelium. He moved to the University of Bordeaux for family reasons and switched from Pharmacology to Cell Biology, with a strong contribution to an introductory course for 1st year university students. Given the important teaching load and the general low level of student engagement in higher education he started to investigate the reasons for student failure (finding out about their expectations and attitudes) and the role of images and animations in comprehension. Scientific publications, web-based multimedia resources and dramatically enhanced retention rates (from 33 to 85%) are the fruits of these activities. At the same time he organized with University College London and Universitat Pompeu Fabra, Barcelona, summer schools on Receptor and Signalling Mechanism. He has been co-director of two European Programmes (Interbio and Transbio) that aimed at enhancing industrial innovation in the biomedical sector in the South West European Region (SUDOE).

For book/publicity purposes, image of the author by #65533; Maarten Kramer

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