Enhanced descriptions from Syndetics:

Authoritative, concise, and current, this bestselling reference in endocrinology--and "all-in-one" text--focuses on the pathophysiology, diagnosis, and treatment of endocrine disorders. Written by recognized authorities and featuring more than 350 two-color illustrations, this edition has been updated to reflect the latest in diagnostic testing and molecular biology as well as new approaches to medical management.

Table of contents provided by Syndetics

• Authors (p. xii)
• Preface (p. xvi)
• 1. Introduction to Endocrinology (p. 1)
• The Endocrine System (p. 2)
• Hormones: Endocrine, Paracrine, & Autocrine Actions (p. 3)
• Chemical Composition of Hormones (p. 3)
• Relationships between Hormones & Other Signaling Molecules (p. 4)
• Neurotransmitters & Hormones (p. 4)
• Vitamins & Hormones (p. 5)
• Oncogenes & Hormones (p. 5)
• The Immune System & Hormones (p. 5)
• Eicosanoids: Prostaglandins & Related Compounds (p. 6)
• Mechanisms of Hormone Action (p. 6)
• Hormone Receptors (p. 6)
• Hormone Effects on Receptor Activity (p. 8)
• Classes of Hormone Action (p. 8)
• Classification of Hormone Action by Receptor Type (p. 8)
• Classification of Hormone Action by Ligand Type (p. 9)
• Mechanisms of Ligand Action (p. 10)
• Regulation of Hormone Responsiveness (p. 11)
• Hormone Responses Can Be Self-Limiting (p. 11)
• Different Signals Influence Hormone Responsiveness (p. 11)
• Modulation of Hormone Levels (p. 12)
• Hormone Synthesis (p. 12)
• Regulation of Hormone Production (p. 12)
• Hormone Transport in the Circulation (p. 13)
• Transport of Hormones across the Membrane (p. 14)
• Metabolism & Elimination of Hormones (p. 14)
• Recombinant DNA, Genomics, Proteomics, & Endocrinology (p. 15)
• Sequencing of the Human Genome (p. 16)
• Genomics & Patterns of Transcription (p. 16)
• Proteomics (p. 16)
• Molecular Basis of Genetic Endocrine Disease (p. 17)
• Evolution of the Endocrine System (p. 17)
• The Origins of Regulatory Chemicals & the Metabolic Code (p. 18)
• Evolution of Hormones & Receptors (p. 18)
• Evolution of Multiple Hormone Response Systems (p. 19)
• Evolution of Endocrine Glands (p. 19)
• Integrative Networks (p. 19)
• Endocrine & Nervous System Relationships: Neuroendocrinology (p. 19)
• Hypothalamic-Pituitary Relationships (p. 20)
• Endocrine Organs & Hormone Production (p. 21)
• Actions of Hormones (p. 21)
• Hormone Release (p. 21)
• Fetal Development (p. 21)
• Cell Growth & Cancer (p. 21)
• Hormonal Effects on Intermediary Metabolism (p. 22)
• Hormonal Effects on Mineral & Water Metabolism (p. 22)
• Hormonal Effects on Cardiovascular & Renal Function (p. 22)
• Hormonal Effects on Skeletal Function (p. 23)
• Hormonal Effects on Reproductive Function (p. 23)
• Hormonal Effects on the Immune System (p. 23)
• Hormonal Effects on the Central Nervous System (p. 23)
• Selective Modulation (p. 24)
• Disorders of the Endocrine System (p. 24)
• Endocrine Hypofunction (p. 25)
• Endocrine Hyperfunction (p. 25)
• Defects in Sensitivity to Hormones (p. 26)
• Syndromes of Hormone Excess Due to Administration of Exogenous Hormone (p. 27)
• Nonendocrine Problems Associated with Endocrine Disease (p. 28)
• Approach to the Patient with Endocrine Disease (p. 28)
• Evidence-Based Endocrinology (p. 28)
• History & Physical Examination (p. 29)
• Laboratory Studies (p. 29)
• Screening for Endocrine Diseases (p. 33)
• Clinical Interpretation of Laboratory Tests (p. 34)
• Treatment of Endocrine Diseases (p. 34)
• Uses of Hormones & Selective Modulators in Therapy of Nonendocrine Disease (p. 35)
• 2. Hormone Synthesis & Release (p. 38)
• Compartmentation of Eukaryotic Cells in Relation to Hormone Synthesis & Release (p. 38)
• Overview of Hormone Biosynthesis (p. 39)
• Membrane Vesicle-Mediated Hormone Export (p. 40)
• Hormone Export Not Mediated by Membrane Vesicles (p. 51)
• Metabolism, Transport, Elimination, & Regulation of Hormones (p. 56)
• 3. Mechanisms of Hormone Action (p. 61)
• Receptors (p. 62)
• Neurotransmitter & Peptide Hormone Receptors (p. 63)
• G Protein-Coupled Receptors (p. 64)
• G Protein Transducers (p. 65)
• G Protein Disorders (p. 66)
• Effectors (p. 67)
• G Protein-Coupled Receptors & Human Disease (p. 68)
• Growth Factor Receptors (p. 70)
• Cytokine Receptors (p. 73)
• Guanylyl Cyclase-Linked Receptors (p. 73)
• Nuclear Action of Peptide Hormones (p. 74)
• Nuclear Receptors (p. 75)
• Steroid Receptor Family (p. 76)
• Thyroid Receptor Family (p. 77)
• Nongenomic Effects of the Steroid Hormones (p. 82)
• Steroid & Thyroid Hormone Receptor Resistance Syndromes (p. 83)
• 4. Endocrine Autoimmunity (p. 85)
• Basic Immune Components & Mechanisms (p. 86)
• Immune Recognition & Response (p. 87)
• Tolerance (p. 90)
• Autoimmunity Is Multifactorial (p. 95)
• Genetic Factors in Autoimmunity (p. 95)
• Environmental Factors in Autoimmunity (p. 96)
• Single Gland Autoimmune Syndromes (p. 96)
• Autoimmune Aspects of Thyroid Disease (p. 97)
• Autoimmune Aspects of Type 1 Diabetes (p. 98)
• Autoimmune Aspects of Other Endocrinopathies (p. 100)
• Autoimmune Polyglandular Syndromes (p. 103)
• Autoimmune Polyglandular Syndrome I (APS-I) (p. 103)
• Autoimmune Polyglandular Syndrome II (APS-II) (p. 103)
• Management of Autoimmune Polyglandular Syndromes (p. 104)
• 5. Hypothalamus & Pituitary Gland (p. 106)
• Hypothalamic Hormones (p. 111)
• Anterior Pituitary Hormones (p. 119)
• ACTH & Related Peptides (p. 119)
• Growth Hormone (p. 120)
• Prolactin (p. 125)
• Thyrotropin (p. 126)
• Gonadotropins: Luteinizing Hormone, Follicle-Stimulating Hormone (p. 128)
• Endocrinologic Evaluation of the Hypothalamic-Pituitary Axis (p. 129)
• Evaluation of ACTH (p. 129)
• Evaluation of Growth Hormone (p. 131)
• Evaluation of Prolactin (p. 132)
• Evaluation of TSH (p. 132)
• Evaluation of LH & FSH (p. 132)
• Problems in Evaluation of the Hypothalamic-Pituitary Axis (p. 133)
• Effects of Pharmacologic Agents on Hypothalamic-Pituitary Function (p. 133)
• Endocrine Tests of Hypothalamic-Pituitary Function (p. 133)
• Neuroradiologic Evaluation (p. 136)
• Pituitary & Hypothalamic Disorders (p. 136)
• Empty Sella Syndrome (p. 138)
• Hypothalamic Dysfunction (p. 139)
• Hypopituitarism (p. 140)
• Pituitary Adenomas (p. 147)
• Posterior Pituitary (p. 163)
• Antidiuretic Hormone (ADH; Vasopressin) (p. 163)
• Oxytocin (p. 164)
• Control of Water Balance (p. 164)
• Diabetes Insipidus (p. 167)
• Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH) (p. 170)
• 6. Growth (p. 176)
• Normal Growth (p. 176)
• Intrauterine Growth (p. 176)
• The Placenta (p. 177)
• Classic Hormones of Growth & Fetal Growth (p. 177)
• Growth Factors & Oncogenes in Fetal Growth (p. 177)
• Insulin-Like Growth Factors, Receptors, & Binding Proteins (p. 177)
• Insulin (p. 178)
• Epidermal Growth Factor (p. 178)
• Fetal Origins of Adult Disease (p. 179)
• Postnatal Growth (p. 179)
• Measurement of Growth (p. 187)
• Skeletal (Bone) Age (p. 191)
• Disorders of Growth (p. 194)
• Short Stature Due to Nonendocrine Causes (p. 194)
• Short Stature Due to Endocrine Disorders (p. 198)
• The Diagnosis of Short Stature (p. 210)
• Tall Stature Due to Nonendocrine Causes (p. 211)
• Beckwith-Wiedemann Syndrome (p. 212)
• Tall Stature Due to Endocrine Disorders (p. 212)
• 7. The Thyroid Gland (p. 215)
• Anatomy & Histology (p. 216)
• Physiology (p. 216)
• Structure of Thyroid Hormones (p. 216)
• Iodine Metabolism (p. 216)
• Thyroid Hormone Synthesis & Secretion (p. 219)
• Abnormalities in Thyroid Hormone Synthesis & Release (p. 224)
• Thyroid Hormone Transport (p. 225)
• Metabolism of Thyroid Hormones (p. 227)
• Control of Thyroid Function (p. 232)
• The Action of Thyroid Hormones (p. 238)
• Physiologic Changes in Thyroid Function (p. 241)
• Thyroid Autoimmunity (p. 243)
• Tests of Thyroid Function (p. 244)
• Tests of Thyroid Hormones in Blood (p. 244)
• Evaluation of the Hypothalamic-Pituitary-Thyroid Axis (p. 245)
• Iodine Metabolism & Biosynthetic Activity (p. 245)
• Thyroid Imaging (p. 247)
• Thyroid Ultrasonography or Magnetic Resonance Imaging (p. 248)
• Thyroid Biopsy (p. 249)
• Effects of Thyroid Hormones on Peripheral Tissues (p. 249)
• Measurement of Thyroid Autoantibodies (p. 250)
• Summary: Clinical Use of Thyroid Function Tests (p. 250)
• Disorders of the Thyroid (p. 251)
• Hypothyroidism (p. 251)
• Hyperthyroidism & Thyrotoxicosis (p. 260)
• Thyroid Hormone Resistance Syndromes (p. 272)
• Nontoxic Goiter (p. 273)
• Thyroiditis (p. 275)
• Effects of Ionizing Radiation on the Thyroid Gland (p. 278)
• Thyroid Nodules & Thyroid Cancer (p. 279)
• 8. Metabolic Bone Disease (p. 295)
• Cellular & Extracellular Calcium Metabolism (p. 295)
• Parathyroid Hormone (p. 296)
• Calcitonin (p. 302)
• Vitamin D (p. 304)
• Integrated Control of Mineral Homeostasis (p. 311)
• Medullary Thyroid Carcinoma (p. 311)
• Hypercalcemia (p. 313)
• Disorders Causing Hypercalcemia (p. 314)
• Treatment of Hypercalcemia (p. 323)
• Hypocalcemia (p. 324)
• Causes of Hypocalcemia (p. 325)
• Treatment of Hypocalcemia (p. 329)
• Bone Anatomy & Remodeling (p. 330)
• Functions of Bone (p. 330)
• Structure of Bone (p. 330)
• Bone Remodeling (p. 332)
• Osteoporosis (p. 335)
• Treatment of Osteoporosis (p. 338)
• Nonpharmacologic Aspects of Osteoporosis Management (p. 343)
• Glucocorticoid-Induced Osteoporosis (p. 343)
• Osteomalacia & Rickets (p. 345)
• Nephrotic Syndrome (p. 348)
• Hepatic Osteodystrophy (p. 349)
• Drug-Induced Osteomalacia (p. 349)
• Hypophosphatemic Disorders (p. 349)
• Calcium Deficiency (p. 351)
• Primary Disorders of the Bone Matrix (p. 351)
• Inhibitors of Mineralization (p. 352)
• Paget's Disease of Bone (Osteitis Deformans) (p. 352)
• Renal Osteodystrophy (p. 357)
• 9. Glucocorticoids & Adrenal Androgens (p. 362)
• Embryology & Anatomy (p. 363)
• Biosynthesis of Cortisol & Adrenal Androgens (p. 364)
• Circulation of Cortisol & Adrenal Androgens (p. 371)
• Metabolism of Cortisol & Adrenal Androgens (p. 371)
• Biologic Effects of Adrenal Steroids (p. 372)
• Glucocorticoids (p. 372)
• Adrenal Androgens (p. 380)
• Laboratory Evaluation (p. 380)
• Disorders of Adrenocortical Insufficiency (p. 384)
• Primary Adrenocortical Insufficiency (Addison's Disease) (p. 384)
• Secondary Adrenocortical Insufficiency (p. 389)
• Diagnosis of Adrenocortical Insufficiency (p. 390)
• Treatment of Adrenocortical Insufficiency (p. 393)
• Prognosis of Adrenocortical Insufficiency (p. 395)
• Cushing's Syndrome (p. 395)
• Hirsutism & Virilism (p. 408)
• Incidental Adrenal Mass (p. 408)
• Glucocorticoid Therapy for Nonendocrine Disorders (p. 410)
• 10. Endocrine Hypertension (p. 414)
• Hypertension of Adrenal Origin (p. 414)
• Synthesis, Metabolism, & Action of Mineralocorticoid Hormones (p. 414)
• Pathogenesis of Mineralocorticoid Hypertension (p. 416)
• Aldosterone & the Heart (p. 417)
• Primary Aldosteronism (p. 417)
• Syndromes Due to Excess Deoxycorticosterone Production (p. 422)
• Cushing's Syndrome (p. 424)
• Pseudohyperaldosteronism (p. 425)
• Type II Pseudohypoaldosteronism (Arnold-Healy-Gordon Syndrome) (p. 427)
• Hypertension of Renal Origin (p. 428)
• The Renin-Angiotensin System (p. 428)
• The Renin-Angiotensin System & Hypertension (p. 431)
• Other Hormone Systems & Hypertension (p. 435)
• Insulin (p. 435)
• Natriuretic Peptides (p. 436)
• Endothelium-Derived Relaxing Factor (p. 436)
• Endothelin (p. 436)
• Kallikrein-Kinin System (p. 437)
• Other Hormones & Autacoids (p. 437)
• Sympathetic Nervous System (p. 437)
• 11. Adrenal Medulla (p. 439)
• History (p. 439)
• Anatomy (p. 440)
• Hormones of the Adrenal Medulla (p. 441)
• Catecholamines (p. 441)
• Other Hormones (p. 451)
• Disorders of Adrenal Medullary Function (p. 451)
• Adrenal Medullary Hypofunction (p. 451)
• Adrenal Medullary Hyperfunction (p. 453)
• Pheochromocytoma (p. 453)
• 12. Testes (p. 478)
• Anatomy & Structure-Function Relationships (p. 478)
• Testes (p. 478)
• Accessory Structures (p. 480)
• Physiology of the Male Reproductive System (p. 480)
• Gonadal Steroids (p. 480)
• Control of Testicular Function (p. 483)
• Evaluation of Male Gonadal Function (p. 484)
• Clinical Evaluation (p. 484)
• Laboratory Tests of Testicular Function (p. 486)
• Pharmacology of Drugs Used to Treat Male Gonadal Disorders (p. 488)
• Androgens (p. 489)
• Gonadotropins (p. 490)
• Gonadotropin-Releasing Hormone (p. 490)
• Clinical Male Gonadal Disorders (p. 490)
• Klinefelter's Syndrome (XXY Seminiferous Tubule Dysgenesis) (p. 491)
• Bilateral Anorchia (Vanishing Testes Syndrome) (p. 493)
• Cryptorchidism (p. 494)
• Noonan's Syndrome (Male Turner's Syndrome) (p. 496)
• Myotonic Dystrophy (p. 497)
• Adult Leydig Cell Failure (Andropause) (p. 499)
• Male Infertility (p. 500)
• Erectile Dysfunction (Impotence) (p. 502)
• Gynecomastia (p. 505)
• Testicular Tumors (p. 508)
• 13. Female Reproductive Endocrinology & Infertility (p. 511)
• Embryology & Anatomy (p. 511)
• Ovarian Steroidogenesis (p. 514)
• Physiology of the Menstrual Cycle (p. 514)
• Menstrual Disturbances (p. 522)
• Hypothalamic Amenorrhea (p. 522)
• Pituitary Amenorrhea (p. 525)
• Ovarian Amenorrhea (p. 528)
• Adrenal Causes of Amenorrhea (p. 535)
• Outflow Tract Disorders (p. 538)
• Menopause (p. 539)
• Oocyte Depletion (p. 540)
• Endocrine System Changes with Aging (p. 541)
• Menopausal Consequences (p. 542)
• Infertility (p. 544)
• Diagnosis of Infertility (p. 545)
• Management of the Infertile Couple (p. 546)
• Contraception (p. 547)
• Oral Contraceptives (p. 548)
• Contraception: Long-Acting Contraceptives (p. 555)
• Emergency Contraception (p. 561)
• 14. Abnormalities of Sexual Determination & Differentiation (p. 564)
• Normal Sex Differentiation (p. 564)
• Testicular & Ovarian Differentiation (p. 569)
• Psychosexual Differentiation (p. 576)
• Abnormal Sex Differentiation (p. 576)
• Seminiferous Tubule Dysgenesis: Chromatin-Positive Klinefelter's Syndrome & Its Variants (p. 576)
• Syndrome of Gonadal Dysgenesis: Turner's Syndrome & Its Variants (p. 579)
• True Hermaphroditism (p. 583)
• Female Pseudohermaphroditism (p. 584)
• P450 Aromatase Deficiency (p. 589)
• Maternal Androgens & Progestogens (p. 589)
• Male Pseudohermaphroditism (p. 589)
• Unclassified Forms of Abnormal Sexual Development in Males (p. 599)
• Unclassified Forms of Abnormal Sexual Development in Females (p. 601)
• Management of Patients with Intersex Problems (p. 601)
• 15. Puberty (p. 608)
• Physiology of Puberty (p. 608)
• Delayed Puberty or Absent Puberty (Sexual Infantilism) (p. 617)
• Precocious Puberty (Sexual Precocity) (p. 628)
• 16. The Endocrinology of Pregnancy (p. 637)
• Conception & Implantation (p. 637)
• Fetal-Placental-Decidual Unit (p. 638)
• Polypeptide Hormones (p. 641)
• Steroid Hormones (p. 642)
• Maternal Adaptation to Pregnancy (p. 643)
• Fetal Endocrinology (p. 647)
• Endocrine Control of Parturition (p. 649)
• Endocrinology of the Puerperium (p. 650)
• Endocrine Disorders & Pregnancy (p. 652)
• Pituitary Disorders (p. 652)
• Pregnancy & Breast Cancer (p. 653)
• Hypertensive Disorders of Pregnancy (p. 654)
• Hyperthyroidism in Pregnancy (p. 655)
• Hypothyroidism in Pregnancy (p. 656)
• 17. Pancreatic Hormones & Diabetes Mellitus (p. 658)
• The Endocrine Pancreas (p. 658)
• Anatomy & Histology (p. 658)
• Hormones of the Endocrine Pancreas (p. 660)
• Diabetes Mellitus (p. 669)
• Classification (p. 669)
• Type 1 Diabetes Mellitus (p. 669)
• Type 2 Diabetes (p. 672)
• Other Specific Types of Diabetes (p. 675)
• Clinical Features of Diabetes Mellitus (p. 678)
• Type 1 Diabetes (p. 678)
• Type 2 Diabetes (p. 679)
• Urinalysis (p. 679)
• Blood Glucose Testing (p. 681)
• Serum Ketone Determinations (p. 682)
• Glycated Hemoglobin Assays (p. 682)
• Lipoproteins in Diabetes (p. 683)
• Diagnosis of Diabetes Mellitus (p. 683)
• Oral Glucose Tolerance Test (p. 684)
• Insulin Levels (p. 684)
• Intravenous Glucose Tolerance Test (p. 685)
• Treatment of Diabetes Mellitus (p. 689)
• Diet (p. 689)
• Oral Agents for the Treatment of Hyperglycemia (p. 690)
• Insulin (p. 698)
• Steps in the Management of the Diabetic Patient (p. 704)
• Acute Complications of Diabetes Mellitus (p. 711)
• Hypoglycemia (p. 711)
• Coma (p. 714)
• Chronic Complications of Diabetes Mellitus (p. 723)
• Specific Chronic Complications of Diabetes Mellitus (p. 725)
• Surgery in the Diabetic Patient (p. 732)
• Diabetics Regulated by Diet Alone (p. 732)
• Diabetics Taking Oral Hypoglycemic Agents (p. 732)
• Diabetics Taking Insulin (p. 732)
• Diabetes Mellitus & Pregnancy (by John L. Kitzmiller, MD) (p. 733)
• Prognosis for Patients with Diabetes Mellitus (p. 741)
• 18. Hypoglycemic Disorders (p. 747)
• Pathophysiology of the Counterregulatory Response to Neuroglycopenia (p. 747)
• Classification of Hypoglycemic Disorders (p. 752)
• Clinical Presentation of Hypoglycemia (p. 753)
• Specific Hypoglycemic Disorders (p. 754)
• Symptomatic Fasting Hypoglycemia with Hyperinsulinism (p. 754)
• Symptomatic Fasting Hypoglycemia without Hyperinsulinism (p. 762)
• Nonfasting Hypoglycemia (Reactive Hypoglycemia) (p. 763)
• 19. Disorders of Lipoprotein Metabolism (p. 766)
• Atherosclerosis (p. 766)
• Overview of Lipid Transport (p. 767)
• Differentiation of Disorders of Lipoprotein Metabolism (p. 771)
• Clinical Descriptions of Primary & Secondary Disorders of Lipoprotein Metabolism (p. 774)
• The Hypertriglyceridemias (p. 774)
• Primary Hypertriglyceridemia (p. 774)
• Secondary Hypertriglyceridemia (p. 778)
• The Primary Hypercholesterolemias (p. 780)
• Familial Hypercholesterolemia (p. 780)
• Familial Combined Hyperlipidemia (p. 781)
• LP(a) Hyperlipoproteinemia (p. 781)
• Familial Ligand-Defective APO B (p. 781)
• Cholesterol 7-[alpha]-Hydroxylase Deficiency (p. 781)
• Secondary Hypercholesterolemia (p. 782)
• Hypothyroidism (p. 782)
• Nephrosis (p. 782)
• Immunoglobulin Disorders (p. 782)
• Anorexia Nervosa (p. 782)
• Cholestasis (p. 782)
• The Primary Hypolipidemias (p. 783)
• Primary Hypolipidemia Due to Deficiency of High-Density Lipoproteins (p. 783)
• Primary Hypolipidemia Due to Deficiency of APO B-Containing Lipoproteins (p. 784)
• Secondary Hypolipidemia (p. 785)
• Other Disorders of Lipoprotein Metabolism (p. 785)
• The Lipodystrophies (p. 785)
• Rare Disorders (p. 786)
• Treatment of Hyperlipidemia (p. 787)
• Dietary Factors in the Management of Lipoprotein Disorders (p. 787)
• Drugs Used in Treatment of Hyperlipoproteinemia (p. 789)
• Bile Acid Sequestrants (p. 789)
• Niacin (Nicotinic Acid) (p. 789)
• Fibric Acid Derivatives (p. 790)
• HMG-CoA Reductase Inhibitors (p. 790)
• Combined Drug Therapy (p. 791)
• Possible Untoward Consequences of Lipid-Lowering Therapy (p. 792)
• 20. Obesity & Overweight (p. 794)
• Controversies & Uncertainties Regarding the Pathogenesis of Obesity (p. 804)
• Survey of Treatment Approaches & Their Efficacy (p. 806)
• Dietary Therapies (p. 806)
• Surgical Treatment of Obesity (p. 807)
• Pharmacologic Therapies (p. 807)
• Other Conditions Affected by Treatment of Obesity or Overweight (p. 810)
• Type 2 Diabetes Mellitus (p. 810)
• Hyperlipidemia (p. 812)
• Polycystic Ovarian Syndrome (p. 812)
• Hypertension (p. 812)
• Gallstones (p. 812)
• Osteoarthritis & Other Weight-Sensitive States (p. 812)
• A Systematic Approach to the Treatment of Obesity (p. 813)
• 21. Humoral Manifestations of Malignancy (p. 814)
• Ectopic Hormone & Receptor Syndromes (p. 814)
• Hypercalcemia of Malignancy (p. 815)
• Ectopic Cushing's Syndrome (p. 819)
• Syndrome of Inappropriate ADH (SIADH) Secretion (p. 822)
• Non-Islet Cell Tumors & Hypoglycemia (p. 823)
• Other Hormones Secreted by Tumors (p. 824)
• Oncogenic Osteomalacia (p. 825)
• Gut Hormones (p. 826)
• 22. Multiple Endocrine Neoplasia (p. 829)
• Multiple Endocrine Neoplasia Type 1 (MEN 1) (p. 829)
• Multiple Endocrine Neoplasia Type 2 (MEN 2) (p. 834)
• Other Disorders Characterized by Multiple Endocrine Organ Involvement (p. 840)
• 23. Geriatric Endocrinology (p. 842)
• Thyroid Function & Disease (p. 842)
• Disorders of the Thyroid Gland (p. 843)
• Carbohydrate Intolerance & Diabetes Mellitus (p. 847)
• Aging & the Physiology of Carbohydrate Intolerance (p. 847)
• Diabetes Mellitus (p. 847)
• Nonketotic Hyperosmolar Coma (p. 849)
• Osteoporosis & Calcium Homeostasis (p. 850)
• Osteoporosis (p. 850)
• Hyperparathyroidism (p. 858)
• Changes in Water Balance (p. 858)
• Hypernatremia (p. 859)
• Hyponatremia (p. 859)
• Hyporeninemic Hypoaldosteronism (p. 859)
• Glucocorticoids & Stress (p. 859)
• Disorders of the Hypothalamic-Pituitary-Adrenal Axis (p. 860)
• Changes in Reproductive Function in Men (p. 861)
• Benign Prostatic Hyperplasia (p. 862)
• 24. Endocrine Emergencies (p. 867)
• Myxedema Coma (p. 867)
• Thyroid Storm (p. 869)
• Thyrotoxic Periodic Paralysis (p. 870)
• Amiodarone Induced Thyrotoxicosis (p. 871)
• Acute Adrenal Insufficiency (p. 872)
• Pituitary Apoplexy (p. 873)
• Diabetic Ketoacidosis (p. 873)
• Nonketotic Hyperosmolar Coma (p. 878)
• Hypercalcemic Crisis (p. 880)
• Acute Hypocalcemia (p. 882)
• Hyponatremia (p. 885)
• Diabetes Insipidus (p. 888)
• 25. AIDS Endocrinopathies (p. 893)
• Thyroid Disorders (p. 893)
• Adrenal Disorders (p. 895)
• Bone & Mineral Disorders (p. 897)
• Gonadal Disorders (p. 897)
• Pituitary Disorders (p. 898)
• Pancreatic Disorders (p. 898)
• Lipid Disorders (p. 899)
• Conclusion (p. 900)
• 26. Endocrine Surgery (p. 902)
• Introduction (p. 902)
• The Thyroid Gland (p. 902)
• Developmental Thyroid Abnormalities (p. 902)
• Hyperthyroidism (p. 903)
• Thyroiditis (p. 904)
• Nodular Goiter (p. 904)
• Thyroid Nodules (p. 904)
• Thyroid Cancer (p. 904)
• Conduct of Thyroidectomy (p. 906)
• The Parathyroid Gland (p. 908)
• Primary Hyperparathyroidism (p. 908)
• Persistent & Recurrent Primary Hyperparathyroidism (p. 910)
• Secondary Hyperparathyroidism (p. 911)
• Special Consideration: Familial Hyperparathyroidism (p. 911)
• Complications of Parathyroid Surgery (p. 911)
• The Adrenal (Suprarenal) Gland (p. 911)
• Primary Hyperaldosteronism (p. 911)
• Hypercortisolism (p. 912)
• Sex Steroid Excess (p. 912)
• Pheochromocytoma (p. 913)
• Adrenal Cortical Carcinoma (p. 913)
• Adrenal Incidentaloma (p. 913)
• Technique of Adrenalectomy (p. 914)
• The Endocrine Pancreas (p. 914)
• Insulinoma (p. 915)
• Gastrinoma (Zollinger-Ellison Syndrome) (p. 916)
• Vipoma (Verner-Morrison) Syndrome (p. 917)
• Glucagonoma (p. 917)
• Somatostatinoma (p. 917)
• Nonfunctioning Pancreatic Tumors (p. 917)
• Appendix Normal Hormone Reference Ranges (p. 920)
• Index (p. 939)