Biocatalysis and biodegradation : microbial transformation of organic compounds / Lawrence P. Wackett and C. Douglas Hershberger.
By: Wackett, Lawrence Philip
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Contributor(s): Hershberger, C. Douglas
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Material type: ![materialTypeLabel](/opac-tmpl/lib/famfamfam/BK.png)
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Item type | Current library | Call number | Copy number | Status | Date due | Barcode | Item holds |
---|---|---|---|---|---|---|---|
General Lending | MTU Bishopstown Library Lending | 572.429 (Browse shelf(Opens below)) | 1 | Available | 00091858 | ||
General Lending | MTU Bishopstown Library Lending | 572.429 (Browse shelf(Opens below)) | 1 | Available | 00091859 |
Enhanced descriptions from Syndetics:
A textbook and resource for professional scientists working in the areas of industrial microbiology, environmental microbiology, and biodegradation.* Details both the fundamental concepts of the microbial transformation of organic compounds as well as its application for biotechnology and biodegradation. * Offers comprehensive coverage of microbial catabolism from the group that developed the online Biocatalysis/Biodegradation Database (http://umbbd.msi.umn.edu/). * Discusses the logic of catabolism, which is important in the context of genome annotation and predicting biodegradation reactions.
Includes bibliographical references and index.
General concepts in biodegradation and biocatalysis -- A history of concepts in biodegradation and microbial catalysis -- Identifying novel microbial catalysis by enrichment culture and screening -- Microbial diversity: catabolism of organic compounds is broadly distributed -- Organic functional group diversity: the unity of biochemistry is dwarfed by its diversity -- Physiological processes: enzymes, emulsification, uptake and chemotaxis -- Evolution of catabolic enzymes and pathways -- Metabolic logic and pathway maps -- Predicting microbial biocatalysis and biodegraduation -- Microbial biotechnology: chemical production and bioremediation -- The impact of genomics on microbial catalysis -- The extent of microbial catalysis and biodegraduation: are microbes infallible -- Big questions and future prospects.
Table of contents provided by Syndetics
- Foreword (p. xi)
- Preface (p. xxi)
- Chapter 1 General Concepts in Biodegradation and Biocatalysis (p. 1)
- Definition of Terms (p. 2)
- Further Resources in Biocatalysis and Biodegradation (p. 5)
- Chapter 2 A History of Concepts in Biodegradation and Microbial Catalysis (p. 7)
- The Beginnings of Biodegradation on Earth (p. 7)
- Early Human Observations of Biodegradation and Biocatalysis (p. 9)
- Early Scientific Studies on Biodegradation and the Spontaneous-Generation Debate (p. 9)
- Microbial Pure Cultures from Nature (p. 12)
- Early History of the Study of Diverse Metabolic Activities of Microbes (p. 13)
- Unity of Metabolism in Living Things (p. 14)
- Oxygen and Oxygenases (p. 15)
- History of Anaerobic Biocatalysis (p. 18)
- Molecular Genetics and Regulation (p. 19)
- Microbes in Organic Synthesis (p. 22)
- Summary (p. 23)
- Chapter 3 Identifying Novel Microbial Catalysis by Enrichment Culture and Screening (p. 27)
- Why Use Enrichment Culture? (p. 28)
- The General Method (p. 30)
- Selection of Conditions and Medium (p. 33)
- Screening for Specific Biocatalytic Reactions (p. 34)
- Summary (p. 35)
- Chapter 4 Microbial Diversity: Catabolism of Organic Compounds Is Broadly Distributed (p. 39)
- The Importance of Microbial (Bio)diversity (p. 39)
- Fungi in Biocatalysis and Biodegradation (p. 41)
- Distribution in the Prokaryotic World of Biodegradative and Novel Biocatalytic Capabilities (p. 43)
- Specialized Biodegradation by Microorganisms with Specialized Metabolisms (p. 52)
- Aerobic versus Anaerobic Microorganisms in Biodegradation (p. 52)
- Representative Microorganisms with Broad Catabolic Abilities (p. 54)
- Microbial Consortia in Biodegradation (p. 61)
- Global Biodegradation and the Supraorganism Concept (p. 62)
- Summary (p. 65)
- Chapter 5 Organic Functional Group Diversity: the Unity of Biochemistry Is Dwarfed by Its Diversity (p. 71)
- Microbial Global Cycling of the Elements (p. 72)
- Facts and Fallacies: Natural Products versus Synthetic Chemicals and Their Biodegradation (p. 74)
- An Organic Functional Group Classification (p. 76)
- Organic Functional Groups Found in Nature (p. 78)
- Ring Compounds Found in Nature (p. 79)
- Organic Functional Groups: What Is Known with Respect to Biodegradation and Microbial Biocatalysis? (p. 88)
- Summary (p. 91)
- Chapter 6 Physiological Processes: Enzymes, Emulsification, Uptake, and Chemotaxis (p. 95)
- General Physiological Responses to Environmental Chemicals (p. 96)
- Enzymes (p. 97)
- Enzyme Substrate Specificity (p. 99)
- Uptake: Getting Substrates to the Enzymes (p. 100)
- Emulsification: Overcoming Poor Availability of Substrate (p. 104)
- Organic-Solvent Resistance (p. 105)
- Chemotaxis: Getting to the Substrates (p. 107)
- Summary (p. 109)
- Chapter 7 Evolution of Catabolic Enzymes and Pathways (p. 115)
- History (p. 116)
- Major Protein Families in Microbial Biocatalysis (p. 118)
- Principles of Evolution Applied to Microbial Catabolism (p. 121)
- Gene Transfer in the Evolution of Catabolic Pathways (p. 125)
- Case Study: Enzyme Evolution in the Aminohydrolase Protein Superfamily (p. 127)
- Summary (p. 131)
- Chapter 8 Metabolic Logic and Pathway Maps (p. 135)
- Overview (p. 135)
- C[subscript 1] Metamap (p. 138)
- C[subscript 2] Metamap (p. 140)
- Cycloalkane Metamap (p. 141)
- BTEX Metamap: Aerobic Metabolism (p. 143)
- BTEX Metamap: Anaerobic Metabolism (p. 145)
- PAH Metamap (p. 145)
- Heterocyclic-Ring Metamap (p. 147)
- Triazine-Ring Metamap (p. 148)
- Organohalogen Metamap (p. 150)
- Organometallic Metamap (p. 152)
- Summary (p. 153)
- Chapter 9 Predicting Microbial Biocatalysis and Biodegradation (p. 157)
- Why Is It Necessary To Predict Biodegradation Pathways? (p. 158)
- Biodegradation Prediction Systems (p. 159)
- Defining the Trunk Pathways (p. 161)
- Defining the Organic Functional Groups Relevant to Microbial Catabolism (p. 163)
- The Basis for Predicting Microbial Biocatalysis and Biodegradation (p. 164)
- Beyond Two Functional Groups: the Need for Heuristics (p. 166)
- Summary (p. 168)
- Chapter 10 Microbial Biotechnology: Chemical Production and Bioremediation (p. 171)
- Historical and Conceptual Progress (p. 171)
- Recent Trends (p. 173)
- End Products of Fermentation: Pharmaceuticals (p. 174)
- Microbial Catalysis To Produce Chiral Products (p. 175)
- Chiral Synthesis of Dichloroprop (p. 178)
- Biocatalysis for Non-Medicinal, Non-Chiral Specialty Chemicals (p. 180)
- Biotechnological Waste Recycling (p. 183)
- Case Study of Bioremediation: Atrazine in Soil (p. 184)
- Summary (p. 189)
- Chapter 11 The Impact of Genomics on Microbial Catalysis (p. 191)
- Genome Sizes and Organization (p. 191)
- The Present Impact of Genomics (p. 197)
- Functional Genomics in the Context of Microbial Biocatalysis (p. 197)
- Inadvertent Deception in Modern Biochemistry Textbooks (p. 202)
- The Case for Reverse Functional Genomics and New Discovery in Biocatalysis (p. 202)
- Summary (p. 203)
- Chapter 12 The Extent of Microbial Catalysis and Biodegradation: Are Microbes Infallible? (p. 205)
- Microbial Enzyme Diversity (p. 206)
- Experiments Suggest that Novel Biocatalytic Reactions Are Ubiquitous (p. 209)
- Enzyme Plasticity and New Biocatalysts (p. 210)
- Summary (p. 211)
- Chapter 13 Big Questions and Future Prospects (p. 213)
- The Questions and Some Thoughts on Their Ultimate Answers (p. 213)
- Summary (p. 216)
- Appendixes
- A. Books and Journals Relevant to Biodegradation and Biocatalysis (p. 217)
- B. Useful Internet Resources in Biodegradation and Biocatalysis (p. 219)
- Index (p. 223)