MTU Cork Library Catalogue

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Biocatalysis and biodegradation : microbial transformation of organic compounds / Lawrence P. Wackett and C. Douglas Hershberger.

By: Wackett, Lawrence Philip.
Contributor(s): Hershberger, C. Douglas.
Material type: materialTypeLabelBookPublisher: Washington, DC : ASM Press, 2001Description: xxiii, 228 p. : ill. ; 29 cm.ISBN: 1555811795.Subject(s): Biodegradation | Biotransformation (Metabolism) | Organic compounds -- BiodegradationDDC classification: 572.429
Contents:
General concepts in biodegradation and biocatalysis -- A history of concepts in biodegradation and microbial catalysis -- Identifying novel microbial catalysis by enrichment culture and screening -- Microbial diversity: catabolism of organic compounds is broadly distributed -- Organic functional group diversity: the unity of biochemistry is dwarfed by its diversity -- Physiological processes: enzymes, emulsification, uptake and chemotaxis -- Evolution of catabolic enzymes and pathways -- Metabolic logic and pathway maps -- Predicting microbial biocatalysis and biodegraduation -- Microbial biotechnology: chemical production and bioremediation -- The impact of genomics on microbial catalysis -- The extent of microbial catalysis and biodegraduation: are microbes infallible -- Big questions and future prospects.
Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
General Lending MTU Bishopstown Library Lending 572.429 (Browse shelf(Opens below)) 1 Available 00091858
General Lending MTU Bishopstown Library Lending 572.429 (Browse shelf(Opens below)) 1 Available 00091859
Total holds: 0

Enhanced descriptions from Syndetics:

A textbook and resource for professional scientists working in the areas of industrial microbiology, environmental microbiology, and biodegradation.* Details both the fundamental concepts of the microbial transformation of organic compounds as well as its application for biotechnology and biodegradation. * Offers comprehensive coverage of microbial catabolism from the group that developed the online Biocatalysis/Biodegradation Database (http://umbbd.msi.umn.edu/). * Discusses the logic of catabolism, which is important in the context of genome annotation and predicting biodegradation reactions.

Includes bibliographical references and index.

General concepts in biodegradation and biocatalysis -- A history of concepts in biodegradation and microbial catalysis -- Identifying novel microbial catalysis by enrichment culture and screening -- Microbial diversity: catabolism of organic compounds is broadly distributed -- Organic functional group diversity: the unity of biochemistry is dwarfed by its diversity -- Physiological processes: enzymes, emulsification, uptake and chemotaxis -- Evolution of catabolic enzymes and pathways -- Metabolic logic and pathway maps -- Predicting microbial biocatalysis and biodegraduation -- Microbial biotechnology: chemical production and bioremediation -- The impact of genomics on microbial catalysis -- The extent of microbial catalysis and biodegraduation: are microbes infallible -- Big questions and future prospects.

Table of contents provided by Syndetics

  • Foreword (p. xi)
  • Preface (p. xxi)
  • Chapter 1 General Concepts in Biodegradation and Biocatalysis (p. 1)
  • Definition of Terms (p. 2)
  • Further Resources in Biocatalysis and Biodegradation (p. 5)
  • Chapter 2 A History of Concepts in Biodegradation and Microbial Catalysis (p. 7)
  • The Beginnings of Biodegradation on Earth (p. 7)
  • Early Human Observations of Biodegradation and Biocatalysis (p. 9)
  • Early Scientific Studies on Biodegradation and the Spontaneous-Generation Debate (p. 9)
  • Microbial Pure Cultures from Nature (p. 12)
  • Early History of the Study of Diverse Metabolic Activities of Microbes (p. 13)
  • Unity of Metabolism in Living Things (p. 14)
  • Oxygen and Oxygenases (p. 15)
  • History of Anaerobic Biocatalysis (p. 18)
  • Molecular Genetics and Regulation (p. 19)
  • Microbes in Organic Synthesis (p. 22)
  • Summary (p. 23)
  • Chapter 3 Identifying Novel Microbial Catalysis by Enrichment Culture and Screening (p. 27)
  • Why Use Enrichment Culture? (p. 28)
  • The General Method (p. 30)
  • Selection of Conditions and Medium (p. 33)
  • Screening for Specific Biocatalytic Reactions (p. 34)
  • Summary (p. 35)
  • Chapter 4 Microbial Diversity: Catabolism of Organic Compounds Is Broadly Distributed (p. 39)
  • The Importance of Microbial (Bio)diversity (p. 39)
  • Fungi in Biocatalysis and Biodegradation (p. 41)
  • Distribution in the Prokaryotic World of Biodegradative and Novel Biocatalytic Capabilities (p. 43)
  • Specialized Biodegradation by Microorganisms with Specialized Metabolisms (p. 52)
  • Aerobic versus Anaerobic Microorganisms in Biodegradation (p. 52)
  • Representative Microorganisms with Broad Catabolic Abilities (p. 54)
  • Microbial Consortia in Biodegradation (p. 61)
  • Global Biodegradation and the Supraorganism Concept (p. 62)
  • Summary (p. 65)
  • Chapter 5 Organic Functional Group Diversity: the Unity of Biochemistry Is Dwarfed by Its Diversity (p. 71)
  • Microbial Global Cycling of the Elements (p. 72)
  • Facts and Fallacies: Natural Products versus Synthetic Chemicals and Their Biodegradation (p. 74)
  • An Organic Functional Group Classification (p. 76)
  • Organic Functional Groups Found in Nature (p. 78)
  • Ring Compounds Found in Nature (p. 79)
  • Organic Functional Groups: What Is Known with Respect to Biodegradation and Microbial Biocatalysis? (p. 88)
  • Summary (p. 91)
  • Chapter 6 Physiological Processes: Enzymes, Emulsification, Uptake, and Chemotaxis (p. 95)
  • General Physiological Responses to Environmental Chemicals (p. 96)
  • Enzymes (p. 97)
  • Enzyme Substrate Specificity (p. 99)
  • Uptake: Getting Substrates to the Enzymes (p. 100)
  • Emulsification: Overcoming Poor Availability of Substrate (p. 104)
  • Organic-Solvent Resistance (p. 105)
  • Chemotaxis: Getting to the Substrates (p. 107)
  • Summary (p. 109)
  • Chapter 7 Evolution of Catabolic Enzymes and Pathways (p. 115)
  • History (p. 116)
  • Major Protein Families in Microbial Biocatalysis (p. 118)
  • Principles of Evolution Applied to Microbial Catabolism (p. 121)
  • Gene Transfer in the Evolution of Catabolic Pathways (p. 125)
  • Case Study: Enzyme Evolution in the Aminohydrolase Protein Superfamily (p. 127)
  • Summary (p. 131)
  • Chapter 8 Metabolic Logic and Pathway Maps (p. 135)
  • Overview (p. 135)
  • C[subscript 1] Metamap (p. 138)
  • C[subscript 2] Metamap (p. 140)
  • Cycloalkane Metamap (p. 141)
  • BTEX Metamap: Aerobic Metabolism (p. 143)
  • BTEX Metamap: Anaerobic Metabolism (p. 145)
  • PAH Metamap (p. 145)
  • Heterocyclic-Ring Metamap (p. 147)
  • Triazine-Ring Metamap (p. 148)
  • Organohalogen Metamap (p. 150)
  • Organometallic Metamap (p. 152)
  • Summary (p. 153)
  • Chapter 9 Predicting Microbial Biocatalysis and Biodegradation (p. 157)
  • Why Is It Necessary To Predict Biodegradation Pathways? (p. 158)
  • Biodegradation Prediction Systems (p. 159)
  • Defining the Trunk Pathways (p. 161)
  • Defining the Organic Functional Groups Relevant to Microbial Catabolism (p. 163)
  • The Basis for Predicting Microbial Biocatalysis and Biodegradation (p. 164)
  • Beyond Two Functional Groups: the Need for Heuristics (p. 166)
  • Summary (p. 168)
  • Chapter 10 Microbial Biotechnology: Chemical Production and Bioremediation (p. 171)
  • Historical and Conceptual Progress (p. 171)
  • Recent Trends (p. 173)
  • End Products of Fermentation: Pharmaceuticals (p. 174)
  • Microbial Catalysis To Produce Chiral Products (p. 175)
  • Chiral Synthesis of Dichloroprop (p. 178)
  • Biocatalysis for Non-Medicinal, Non-Chiral Specialty Chemicals (p. 180)
  • Biotechnological Waste Recycling (p. 183)
  • Case Study of Bioremediation: Atrazine in Soil (p. 184)
  • Summary (p. 189)
  • Chapter 11 The Impact of Genomics on Microbial Catalysis (p. 191)
  • Genome Sizes and Organization (p. 191)
  • The Present Impact of Genomics (p. 197)
  • Functional Genomics in the Context of Microbial Biocatalysis (p. 197)
  • Inadvertent Deception in Modern Biochemistry Textbooks (p. 202)
  • The Case for Reverse Functional Genomics and New Discovery in Biocatalysis (p. 202)
  • Summary (p. 203)
  • Chapter 12 The Extent of Microbial Catalysis and Biodegradation: Are Microbes Infallible? (p. 205)
  • Microbial Enzyme Diversity (p. 206)
  • Experiments Suggest that Novel Biocatalytic Reactions Are Ubiquitous (p. 209)
  • Enzyme Plasticity and New Biocatalysts (p. 210)
  • Summary (p. 211)
  • Chapter 13 Big Questions and Future Prospects (p. 213)
  • The Questions and Some Thoughts on Their Ultimate Answers (p. 213)
  • Summary (p. 216)
  • Appendixes
  • A. Books and Journals Relevant to Biodegradation and Biocatalysis (p. 217)
  • B. Useful Internet Resources in Biodegradation and Biocatalysis (p. 219)
  • Index (p. 223)

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