Medical microbiology / Cedric A. Mims, John HL Playfair, Ivan M. Roitt, Derek Wakelin, Rosamund Williams ; with a contribution from Roy M. Anderson.

By: Mims, Cedric A [author].

Contributor(s): Playfair, J. H. L [author] | Roitt, Ivan M. (Ivan Maurice) [author] | Wakelin, Derek [author] | Williams, Rosamund J [author] | Anderson, Roy M .

Material type: materialTypeLabel

BookPublisher: St. Louis : Mosby, 1993Description: Various pagings : illustrations (chiefly color), tables ; 30 cm.Content type: text Media type: unmediated Carrier type: volumeISBN: 0397446314 (paperback).Subject(s): Medical microbiology

DDC classification: 616.9041

Contents:

The adversaries: Microbes -- Microbes and parasites -- The host-parasite relationship -- The organisms -- Host defence mechanisms -- The innate defences of the body -- Adaptive responsibility provide a quantum leap in effective defence -- The basis of antigen recognition -- The cellular basis of adaptive immune responses -- Assessment of host defence systems and microbial antigens -- Immunological reactions producing tissue damage -- Conflicts: Conflicts: the background to infectious disease -- Entry, exit and transmission -- Natural defence in action -- Spread and replication -- Adaptive immunity in action -- Parasite survival strategies and persistent infections -- Pathological consequences of infection -- Diagnosis and clinical manifestations: Diagnostic principles -- General principles and specimen quality -- Microbiological techniques for the diagnosis of infection -- System infection: The clinical manifestations of infection: an introduction -- Upper respiratory tract infections -- Infections of the eye -- Lower respiratory tract infections -- Urinary tract infections -- Sexually transmitted infections -- Gastrointestinal tract infections -- Obstetric and perinatal infections -- Central nervous system infections -- Infections of the skin, muscle, joints, bone and haemopoietic system -- Multisystem and other infections: World-wide virus infections -- Vector-borne infections -- Multisystem zoonoses -- Pyrexia of unknown origin -- Infection in the compromised host -- Control: Strategies for control: an introduction -- Antimicrobial agents and chemotherapy -- Vaccination -- Passive and non-specific immunotherapy -- Epidemiological aspects of the control of infection and disease -- Hospital infection, sterilization and disinfection.

Holdings
Item type	Current library	Call number	Copy number	Status	Date due	Barcode	Item holds
General Lending	MTU Bishopstown Library Store Item	616.9041 (Browse shelf(Opens below))	1	Available		00019175

Total holds: 0

Enhanced descriptions from Syndetics:

This volume reflects current changes in teaching practice, emphasizing the conflict between man and microbe. Sections describe the adversaries, the conflicts, the consequences of the conflicts, and strategies for control at individual, hospital and community level.

Includes bibliographical references and index.

Table of contents provided by Syndetics

I The Adversaries: Parasites
1 Microbes as Parasites
The Varieties of Microbes
Living Inside or Outside Cells
Systems of Classification
The Organisms
2 Bacteria
3 Viruses
4 Fungi
5 Protozoa
6 Helminths and Arthropods
7 Prions
8 The Host-Parasite Relationship
The Normal Flora
Symbiotic Association
The Characteristics of Parasitism
The Evolution of Parasitism
II The Adversaries: Host Defenses
9 The Innate Defenses of the Body
Defense Against Entry into the Body
Defenses Once the Microorganism Penetrates the Body
10 Adaptive Responses - a Quantum Leap in Effective Defense
The Role of Antibodies
The Role of T Lymphocytes/MHC
Extracellular Attack on Large Infectious Agents
Local Defenses at Mucosal Surfaces
11 The Cellular Basis of Adaptive Immune Responses
B and T Cell Receptors
Selection & Clonal Expansion of Lymphocytes
Role of Memory Cells
T-independent and T-dependent Antigens
Cytokines
Regulatory Mechanisms
Tolerance Mechanisms
III Conflicts
12 Conflicts: Background to Infectious Disease
Host-Parasite Relationships
Causes of Infectious Diseases
The Biologic Response Gradient
13 Entry, Exit and Transmission
Sites of Entry
Exit and Transmission
Types of Transmission
Transmission from Animals
14 Innate Defenses in Action
Complement
C-reactive Protein
Phagocytosis
Cytotoxicity by Lymphocytes and Natural Killer Cells
Cytotoxic Lipids
Cytokines
Fever
15 Spread and Replication
Features of Surface and Systemic Infections
Mechanisms of Spread through the Body
Genetic Determinants of Spread and Replication
Other Factors Affecting Spread and Replication
16 Adaptive Immunity in Action
17 Parasite Survival Strategies and Persistent Infections
Parasite Survival Strategies
Concealment of Antigens
Antigenic Variation
Immunosuppression
Persistent Infections
18 Pathologic Consequences of Infection
Pathology Due to Direct Effects of the Microorganism
Pathologic Activation of Innate Immune Mechanisms
Pathologic Consequences of the Adaptive Immune Response
Skin Rashes
Viruses and Cancer
Microbes & Diseases of obscure origin
IV Clinical Manifestations And Diagnosis Of Infections By Body System
19 Upper Respiratory Tract Infections
The Clinical Manifestations of Infection
The Common Cold
Pharyngitis and Tonsillitis
Otitis and Sinusitis
Acute Epiglottitis
Oral Cavity Infections
Laryngitis and Tracheitis
Diphtheria
Summary
20 Lower Respiratory Tract Infections
Acute Infections of the Lower Respiratory Tract
Chronic Infections of the Lower Respiratory Tract
Parasitic Infections of the Lower Respiratory Tract
Summary
21 Urinary Tract Infections
Acquisition and Etiology
Pathogenesis of UTIs
Clinical Features and Complications
Laboratory Diagnosis of UTIs
Treatment of UTIs
Prevention of Urinary Tract Infections
Summary
22 Sexually Transmitted Diseases
STDs and Sexual Behavior
Syphilis
Gonorrhea
Chlamydial Infection
Other Causes of Inguinal Lymphadenopathy
Mycoplasmas and Non-gonococcal Urethritis
Other Causes of Vaginitis and Urethritis
Genital Herpes
Human Papillomavirus Infection
HIV and AIDS
Opportunistic STDs
Arthropod Infestations
Summary
23 Gastrointestinal Tract Infections
Diarrheal Diseases
Helicobacter pylori and Gastric Ulcer Disease
Parasites and the Gastrointestinal Tract
Systemic Infection Initiated in the Gastrointestinal Tract
Hepatitis & other diseases of liver
Summary
24 Obstetric and Perinatal Infections
Infections Occurring in Pregnancy
Congenital Infections
Infections Occurring Around the Time of Birth
25 Central Nervous System Infections
Invasion of the Central Nervous System
The Body's Response to Invasion
Bacterial Meningitis
Fungal Meningitis
Protozoal Meningitis
Viral Meningitis
Encephalitis
Neurologic Diseases of Possible Viral Etiology
Slow Virus Infection
Brain Absceses
Encephalopathy Due to Scrapie-type Agents
Postvaccinial and Postinfectious Encephalitis
CNS Disease Due to Helminth Parasties
Tetanus and Botulism
Summary
26 Infections of the Eye
Conjunctivitis
Infection of the Deeper Layers of the Eye
27 Infections of Skin
Infections of the Skin
Bacterial Infections of Skin, Soft Tissue and Muscle
Mycobacterial Diseases of the Skin
Fungal Infections of the Skin
Parasitic Infections of the Skin
Mucocutaneous Lesions Caused by Viruses
Other Infectious Causes of Maculopapular Rashes
Summary
28 Infections of Muscle, Joints, Bone and Hemopoietic System
Kawasaki Syndrome
Muscle infections
Joint and Bone Infections
Infections of the Hemopoietic System
29 Worldwide Virus Infections
Measles
Mumps
Rubella
Cytomegalovirus Infection
EBV Infection
Other Human Herpesvirus (HHV) Infections
Smallpox
Summary
30 Vector-borne Infections
Arboviruses and Hemorrhagic Fevers
Rickettsial Infections
Borrelia Infections
Protozoal Infections
Helminth Infections
31 Zoonoses
Arenavirus Infections
Korean Hemorrhagic Fever
Marburg and Ebola Hemorrhagic Fevers
Q Fever
Anthrax
Plague
Yersinia enterocolitica Infection
Tularemia
Pasteurella multocida Infection
Leptospirosis
Rat Bite Fever
Brucellosis
Helminth Infections
32 Fever of Unknown Origin
Definitions of Fever of Unknown Origin
Causes of FUO
Investigation of Classical FUO
Treatment of FUO
FUO in Specific Patient Groups
Infective Endocarditis
Summary
33 Infections in the Compromised Host
The Compromised Host
Deficient Innate Immunity
Deficient Adaptive Immunity
Pathogens that Infect the Compromised Host
Clinical management of compromised host
Summary
V Diagnosis And Control
34 Strategies for Control: An Introduction
Epidemiologic considerations
Importance of diagnosis
Chemotherapy Versus Vaccination
Control Versus Eradication
35 Diagnosis of Infection and Assessment of Host Defense Mechanisms
Aims of the Clinical Microbiology Laboratory
Specimen Protocols
Non-cultural Techniques for the Laboratory Diagnosis of Infection
Cultivation (Culture) of Microorganisms
Identification of Microorganisms Grown in Culture
Antibody Detection Methods for the Diagnosis of Infection
Assessment of Host Defense Systems
36 Attacking the Enemy: Antimicrobial Agents and Chemotherapy
Selective Toxicity Discovery and Design of Antimicrobial Agents
Classification of Antibacterial Agents
Inhibitors of Cell Wall Synthesis
Inhibitors of Protein Synthesis
Inhibitors of Nucleic Acid Synthesis
Other Agents That Affect DNA
Inhibitors of Cytoplastic Membrane Function
Antibacterial Agents in Practice
Antiviral Agents
Antifungal and Antiparasitic Agents
Use and Misuse of Antimicrobial Agents
Resistance to Antimicrobials
Summary
37 Boosting Host Defense: Vaccination
The Aims of Vaccination
Requirements of a Good Vaccine
Types of Vaccine
Special Considerations
Current Vaccine Practice
Community-based Control by Vaccination
Factors Influencing the Success of Vaccination
38 Passive and Non-specific Immunotherapy
Passive Immunization with Antibody
Non-specific Cellular Immunostimulation
Correction of Host Immunodeficiency
39 Hospital Infection: Sterilization and Disinfection
Common Hospital-acquired Infections
Important Causes of Hospital Infection
Sources and Routes of Spread of Hospital Infection
Host Factors and Hospital Infection
The Consequences of Hospital Infection
Prevention of Hospital Infection
Investigating Hospital Infection
Sterilization and Disinfection
Deciding Whether Sterilization or Disinfection Should Be Used
Techniques for Sterilization
Controlling Sterilization and Disinfection
Summary
Pathogen Review
Answers
Index
Appendix I Protocols for Specimen Processing
Protocols for Specimen Processing
Specimen Collection
Transport of Specimens
Specimen Processing

Medical microbiology / Cedric A. Mims, John HL Playfair, Ivan M. Roitt, Derek Wakelin, Rosamund Williams ; with a contribution from Roy M. Anderson.

By: Mims, Cedric A [author].

Contributor(s): Playfair, J. H. L [author] | Roitt, Ivan M. (Ivan Maurice) [author] | Wakelin, Derek [author] | Williams, Rosamund J [author] | Anderson, Roy M.

Enhanced descriptions from Syndetics:

Table of contents provided by Syndetics

Contributor(s): Playfair, J. H. L [author] | Roitt, Ivan M. (Ivan Maurice) [author] | Wakelin, Derek [author] | Williams, Rosamund J [author] | Anderson, Roy M .