A primer of drug action : a concise, nontechnical guide to the actions, uses, and side effects of psychoactive drugs / Robert M. Julien.
By: Julien, Robert M.
Material type: BookPublisher: New York : W.H. Freeman, 1998Edition: 8th ed.Description: xiv, 548 p. : ill. ; 24 cm. + hbk.ISBN: 0716731126 ; 0716731134 .Subject(s): Psychotropic drugs | PsychopharmacologyDDC classification: 615.78Item type | Current library | Call number | Copy number | Status | Date due | Barcode | Item holds |
---|---|---|---|---|---|---|---|
General Lending | MTU Bishopstown Library Lending | 615.78 (Browse shelf(Opens below)) | 1 | Available | 00069655 |
Enhanced descriptions from Syndetics:
The 1997 edition which surveys the psychoactive drugs currently available and looks at their effects on the brain and behaviour. Aimed at students of pharmacology, neuropsychopharmacology and psychology.
Previous ed.: 1995.
Includes bibliographical references and index.
Principles of drug action -- Central nervous system depressants: traditional sedative-hypnotic drugs and antiepileptic drugs -- Central nervous system depressants: alcohol and the inhalants of abuse -- Drug treatment of anxiety disorders: benzodiazepines and "second-generation" anxiolytics -- Psychostimulants: cocaine and the amphetamines -- Psychostimulants: caffeine and nicotine -- Antidepressant drugs: four decades of continuing progress -- Pharmacotherapy of bipolar disorder: antimanic drugs -- Antipsychotic drugs: conventional and new-generation agents -- Opioid analgesics -- Marijuana: a unique sedative-euphoriant-psychedelic drug -- Psychedelic drugs: mescaline, LSD, phencyclidine and other hallucinogens -- Anabolic-androgenic steroids -- Drugs and society: priorities and alternatives -- Integration of drugs and psychological therapies in treating mental and behavior disorders.
Table of contents provided by Syndetics
- Preface (p. xi)
- Part 1 Introduction to Psychopharmacology: How Drugs Interact with the Body and the Brain (p. 1)
- 1 Pharmacokinetics: How Drugs Are Handled by the Body (p. 3)
- Drug Absorption
- Drug Distribution
- Termination of Drug Action
- Time Course of Drug Distribution and Elimination: Concept of Drug Half-Life
- Drug Half-Life, Accumulation, and Steady State
- Therapeutic Drug Monitoring
- Drug Tolerance and Dependence
- 2 Pharmacodynamics: How Drugs Act (p. 37)
- Receptors for Drug Action
- Dose-Response Relationships
- Drug Safety and Effectiveness
- 3 The Neuron, Synaptic Transmission, and Neurotransmitters (p. 60)
- Overall Organization of the CNS
- The Neuron
- Specific Neurotransmitters
- Part 2 Drugs That Depress Brain Function: Sedative-Hypnotic Drugs (p. 89)
- 4 Ethyl Alcohol and the Inhalants of Abuse (p. 91)
- Ethyl Alcohol
- Pharmacology of Alcohol
- Alcoholism and Its Pharmacological Treatment
- Inhalants of Abuse
- Why Inhalants Are Abused and Who Abuses Them
- Acute Intoxication and Chronic Effects
- Chapter 4 Appendix: What Is a Drink? How Much Alcohol Is in My Drink?
- 5 Barbiturates, General Anesthetics, Gamma Hydroxybutyrate (GHB), and Antiepileptic Drugs (p. 140)
- Historical Background
- Sites and Mechanisms of Action
- Sedative-Induced Brain Dysfunction
- Specific Depressants
- Barbiturates
- Nonbarbiturate Sedative-Hypnotic Drugs
- General Anesthetics
- Gamma Hydroxybutyrate
- Antiepileptic Drugs
- Relationships Between Structure and Activity
- Specific Agents
- Antiepileptic Drugs in Pregnancy
- 6 Benzodiazapines and Second-Generation Anxiolytics (p. 164)
- Benzodiazepines
- What Is a Benzodiazapine?
- Mechanism of Action: Benzodiazepine-GABA Receptor
- Pharmacokinetics
- Pharmacological Effects
- Clinical Uses and Limitations
- Side Effects and Toxicity
- Tolerance and Dependence
- Effects in Pregnancy
- Flumazenil: A GABA[subscript A] Antagonist
- Second-Generation Anxiolytics
- Zolpidem
- Zaleplon and Zopiclone
- Partial Agonists at GABA[subscript A] Receptors
- Serotoninergic Anxiolytics
- Anticonvulsants as Anxiolytics
- Part 3 Drugs That Stimulate Brain Function: Psychostimulants (p. 189)
- 7 Cocaine and the Amphetamines (p. 190)
- Cocaine
- Forms of Cocaine
- Pharmacokinetics
- Mechanism of Action
- Pharmacological Effects in Human Beings
- Comorbidity
- Cocaine and Pregnancy
- Neurotoxicity of Cocaine
- Pharmacological Treatment of Cocaine Dependency
- Psychosocial Interventions for Cocaine Dependence
- Amphetamines
- Mechanism of Action
- Pharmacological Effects
- Dependence and Tolerance
- Ice: A Free-Base Form of Methamphetamine
- Methamphetamine Neurotoxicity
- Nonamphetamine Behavioral Stimulants
- 8 Caffeine and Nicotine (p. 225)
- Caffeine
- Pharmacokinetics
- Pharmacological Effects
- Mechanism of Action
- Reproductive Effects
- Tolerance and Dependence
- Nicotine
- Pharmacokinetics
- Pharmacological Effects
- Mechanism of Action
- Tolerance and Dependence
- Toxicity
- Therapy for Nicotine Dependence
- Chapter 8 Appendix: Caffeine Content in Beverages, Foods, and Medicines
- Part 4 Drugs That Are Used to Treat Psychological Disorders (p. 253)
- 9 Antidepressant Drugs (p. 255)
- Depression
- First-Generation Antidepressants
- Second-Generation (Atypical) Antidepressants
- Selective Serotonin Reuptake Inhibitors
- Dual-Action Antidepressants
- Selective Norepinephrine Reuptake Inhibitors
- Antidepressants of the Future
- 10 Drugs Used to Treat Bipolar Disorder (Mood Stabilizers) (p. 306)
- Bipolar Disorder
- Lithium
- Neuromodulator Anticonvulsants
- Atypical Antipsychotics
- Acetylcholinesterase Inhibitors
- Omega-3 Fatty Acids
- Miscellaneous Agents
- Psychotherapeutic and Psychosocial Treatments
- 11 Antipsychotic Drugs (p. 337)
- Schizophrenia
- Overview of Antipsychotic Drugs
- Phenothiazines
- Older Alternatives to Phenothiazines
- Atypical Antipsychotic Agents
- 12 Child and Adolescent Psychopharmacology (p. 382)
- Behavioral and Aggressive Disorders
- Autism and Other Pervasive Developmental Disorders
- Attention Deficit Hyperactivity Disorder
- Depression in Children and Adolescents
- Anxiety Disorders in Children and Adolescents
- Bipolar Disorder in Children and Adolescents
- Psychotic Disorders in Children and Adolescents
- 13 Geriatric Psychopharmacology: Drugs for Parkinsonism and Alzheimer's Disease (p. 421)
- Parkinson's Disease
- Levodopa
- Dopamine Receptor Agonists
- Selegiline
- Muscarinic Receptor Antagonists
- Amantadine and Memantine
- CEP-1347
- Alzheimer's Disease
- Acetylcholinesterase Inhibitors
- Memantine
- Investigational Drugs
- Part 5 Special Topics in Psychotherapeutics (p. 443)
- 14 Nonnarcotic Anti-Inflammatory Analgesics (p. 444)
- Nonselective Cyclooxygenase Inhibitors
- Selective COX-2 Inhibitors
- Nonopioid Analgesics of the Future: Nitric Oxide-Releasing Aspirins
- 15 Opioid Analgesics (p. 461)
- History of Opioid Analgesics
- Terminology
- Opioid Receptors
- Classification of Opioid Analgesics
- Morphine: A Pure Opioid Agonist
- Other Pure Opioid Agonists
- Partial Opioid Agonists
- Mixed Agonist-Antagonist Opioids
- Pure Opioid Antagonists
- Opioid Combinations
- Pharmacotherapy of Opioid Dependence
- 16 Herbal Medicines Used in the Treatment of Psychological Disorders (p. 501)
- St. John's Wort
- Ginkgo
- Kava
- Ephedrine (Ma-Huang)
- Other Herbals That Act on the CNS
- 17 Integration of Drugs and Psychological Therapies in Treating Mental and Behavior Disorders (p. 524)
- Undertreatment of Mental and Psychological Disorders
- Depression
- Role of Drugs as Cotherapy
- Role of Psychotherapy as Cotherapy
- Role of the Treatment Team
- DSM-IV-TR Classification of Mental Disorders
- Part 6 Agents Primarily Considered as Drugs of Abuse (p. 555)
- 18 Tetrahydrocannabinol (p. 556)
- History
- Mechanism of Action: Cannabinoid Receptor
- Pharmacokinetics
- Pharmacological Effects of THC in Animals
- Pharmacological Effects of THC in Humans
- Tolerance and Dependence
- Therapeutic Uses
- Cannabinoid Antagonists
- 19 Psychedelic Drugs: Mescaline, Ecstasy, LSD, and Other Hallucinogens (p. 588)
- Anticholinergic Psychedelics: Scopolamine
- Catecholaminelike Psychedelics
- Serotoninlike Psychedelics
- Glutaminergic NMDA Receptor Antagonists
- Opioid Kappa Receptor Agonist: Salvinorin A
- 20 Anabolic Steroids (p. 626)
- Mechanism of Action
- Effects
- Physical Dependence
- Abuse and Treatment
- Androstenedione
- 21 Topics in Drug Abuse (p. 645)
- Historical and Current Perspectives
- Extent of the Drug Problem
- Nosology and Psychopathology of Substance Abuse
- Psychoactive Drugs as Behavioral Reinforcers: The Neurobiology of Addiction
- Other Neurotransmitter Systems Involved in Reward: Modulators of Dopaminergic Activity
- Drug Availability
- Addiction as a Chronic, Relapsing Illness
- Drug Education
- Treatment Issues
- Pharmacotherapy of Substance Use Disorders
- Glossary (p. 667)
- Index (p. 675)