MTU Cork Library Catalogue

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Organic chemistry of drug synthesis. Vol. 4 / Daniel Lednicer ... [et al.].

By: Lednicer, Daniel, 1929-.
Contributor(s): Mitscher, Lester A | Georg, Gunda I.
Material type: materialTypeLabelBookPublisher: Chichester : Wiley, 1990Description: xiii, 253 p. : ill. ; 24 cm. + hbk.ISBN: 0471855480 .Subject(s): Pharmaceutical chemistry | Drugs | Organic compounds -- SynthesisDDC classification: 615.19
Contents:
Aliphatic and alicyclic compounds -- Monocyclic aromatic compounds -- Polycyclic aromatic compounds and their reduction products -- Steroids -- Five-membered ring heterocycles -- Six-membered ring heterocycles -- Five-membered ring benzofused heterocycles -- Six-membered ring benzofused heterocycles -- Bicyclic fused heterocycles -- Lactam antibiotics -- Miscellaneous heterocycles.
Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
General Lending MTU Bishopstown Library Lending 615.19 (Browse shelf(Opens below)) 1 Available 00075917
Total holds: 0

Enhanced descriptions from Syndetics:

Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Includes index.

Aliphatic and alicyclic compounds -- Monocyclic aromatic compounds -- Polycyclic aromatic compounds and their reduction products -- Steroids -- Five-membered ring heterocycles -- Six-membered ring heterocycles -- Five-membered ring benzofused heterocycles -- Six-membered ring benzofused heterocycles -- Bicyclic fused heterocycles -- Lactam antibiotics -- Miscellaneous heterocycles.

Table of contents provided by Syndetics

  • Preface (p. xi)
  • 1 Open-Chain Compounds (p. 1)
  • 1 Peptidomimetic Compounds (p. 2)
  • A Antiviral Protease Inhibitors (p. 2)
  • 1 Human Immunodeficiency Virus (p. 2)
  • 2 Human Rhinovirus j (p. 9)
  • 2 Miscellaneous Peptidomimetic Compounds (p. 11)
  • References (p. 19)
  • 2 Alicyclic Compounds (p. 21)
  • 1 Monocyclic Compounds (p. 21)
  • A Prostaglandins (p. 21)
  • B Antiviral Agents (p. 25)
  • C Miscellaneous Monocyclic Compounds (p. 29)
  • 2 Polycyclic Compounds: Steroids (p. 31)
  • A 19-Nor Steroids (p. 31)
  • B Corticosteroid Related Compounds (p. 34)
  • 3 Polycyclic Compounds / (p. 38)
  • References (p. 40)
  • 3 Monocyclic Aromatic Compounds (p. 43)
  • 1 Arylcarbonyl Derivatives (p. 43)
  • 2 Biphenyls (p. 47)
  • 3 Compounds Related to Aniline (p. 50)
  • 4 Compounds Related to Arylsulfonic Acids (p. 53)
  • 5 Diarylmethanes (p. 58)
  • 6 Miscellaneous Monocyclic Aromatic Compounds (p. 60)
  • References (p. 67)
  • 4 Carbocyclic Compounds Fused to a Benzene Ring (p. 69)
  • 1 Indenes (p. 69)
  • 2 Naphthalenes (p. 73)
  • 3 Tetrahydronaphthalenes (p. 74)
  • 4 Other benzofused carbocyclic compounds (p. 79)
  • References (p. 81)
  • 5 Five-Membered Heterocycles (p. 83)
  • 1 Compounds with One Heteroatom (p. 83)
  • 2 Compounds with Two Heteroatoms (p. 91)
  • A Oxazole and Isoxazoles (p. 91)
  • B Imidazoles and a Pyrrazole (p. 94)
  • C Thiazoles (p. 99)
  • D Triazoles (p. 103)
  • E Tetrazoles (p. 109)
  • References (p. 112)
  • 6 Six-Membered Heterocycles (p. 115)
  • 1 Compounds with One Heteroatom (p. 115)
  • A Pyridines (p. 115)
  • B Reduced Pyridines (p. 117)
  • C Miscellaneous (p. 119)
  • 2 Compounds with Two Heteroatoms (p. 121)
  • A Pyrimidines (p. 121)
  • B Miscellaneous Six-Membered Heterocycles (p. 133)
  • References (p. 136)
  • 7 Five-Membered Heterocycles Fused to One Benzene Ring (p. 139)
  • 1 Compounds with One Heteroatom (p. 139)
  • A Benzofurans (p. 139)
  • B Indoles (p. 141)
  • C Indolones (p. 148)
  • D Miscellaneous Compounds with One Heteroatom (p. 153)
  • 2 Five-Membered Rings with Two Heterocyclic Atoms (p. 156)
  • A Benzimidazoles (p. 156)
  • B Miscellaneous Compounds (p. 158)
  • References (p. 160)
  • 8 Six-Membered Heterocycles Fused to One Benzene Ring (p. 163)
  • 1 Compounds with One Heteroatom (p. 163)
  • A Benzopyrans (p. 163)
  • B Quinolines and Their Derivatives (p. 167)
  • C Quinolone Antibacterial Agents (p. 172)
  • 2 Compounds with Two Heteroatoms (p. 176)
  • A Benzoxazines (p. 176)
  • B Quinazolines (p. 178)
  • C Miscellaneous Benzo-Fused Heterocycles (p. 184)
  • References (p. 186)
  • 9 Bicyclic Fused Heterocycles (p. 189)
  • 1 Compounds with Five-Membered Rings Fused to Six-Membered Rings (p. 189)
  • A Compounds with Two Heteroatoms (p. 189)
  • B Compounds with Three Heteroatoms (p. 191)
  • C Compounds with Four Heteroatoms (p. 195)
  • 2 Compounds with Two Fused Six-Membered Rings (p. 208)
  • 3 Miscellaneous Compounds with Two Fused Heterocyclic Rings: Beta Lactams (p. 213)
  • References (p. 215)
  • 10 Polycyclic Fused Heterocycles (p. 217)
  • 1 Compounds with Three Fused Rings (p. 217)
  • 2 Compounds with Four Fused Rings (p. 228)
  • 3 Compounds with Five or More Fused Rings: Camptothecins (p. 230)
  • References (p. 232)
  • Subject Index (p. 233)
  • Cross Index of Biological Activity (p. 241)
  • Cumulative Index (p. 245)

Author notes provided by Syndetics

Daniel Lednicer, PhD, was a project officer at the National Cancer Institute

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