MTU Cork Library Catalogue

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Protein therapeutics [electronic book] / edited by Zuben Sauna and Chava Kimchi-Sarfaty.

Contributor(s): Sauna, Zuben E [editor] | Kimchi-Sarfaty, Chava [editor].
Material type: materialTypeLabelBookSeries: Topics in medicinal chemistry (Springer (Firm)): Publisher: Cham, Switzerland: Springer, [2017]Copyright date: ©2017Description: online resource (xiii, 182 pages) : illustrations (some color), tables.Content type: text Media type: computer Carrier type: online resourceISBN: 9783319418162 (hardback); 9783319418186 (e-Book).Subject(s): Protein drugs | Biomedical engineering | Biochemistry | ChemistryDDC classification: 615.19 Online resources: e-Book
Contents:
Protein production in Eukaryotic cells / Kripa Ram, Diane Hatton, Sanjeev Ahuja, Jean Bender, Alan Hunter and Richard Turner -- Production of protein therapeutics in the quality y design (QbD) paradigm / Anurag Rathore and Sumit Singh -- Characterization of therapeutic proteins / E B Struble, N Kirschbaum, J Liu, E Marszal, and M Shapiro -- Immunogenicity lessons learned from the clinical development of Vatreptacog Alfa, a recombinant activated factor viii analog, in hemophilia with inhibitors / Kasper Lamberth, Karin Nana Weldingh, Silke Ehrenforth, Mette Ribel Chehade, and Henrik Ostergaare -- The art of gene redesign and recombinant protein production: approaches and perspectives / Anton Komar.

Enhanced descriptions from Syndetics:

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactionson the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors

Includes bibliographical references and index.

Protein production in Eukaryotic cells / Kripa Ram, Diane Hatton, Sanjeev Ahuja, Jean Bender, Alan Hunter and Richard Turner -- Production of protein therapeutics in the quality y design (QbD) paradigm / Anurag Rathore and Sumit Singh -- Characterization of therapeutic proteins / E B Struble, N Kirschbaum, J Liu, E Marszal, and M Shapiro -- Immunogenicity lessons learned from the clinical development of Vatreptacog Alfa, a recombinant activated factor viii analog, in hemophilia with inhibitors / Kasper Lamberth, Karin Nana Weldingh, Silke Ehrenforth, Mette Ribel Chehade, and Henrik Ostergaare -- The art of gene redesign and recombinant protein production: approaches and perspectives / Anton Komar.

MTU CORK Module BIOT 8005 - Core reading.

Electronic reproduction.: ProQuest LibCentral. Mode of access: World Wide Web.

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